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Published: 2025-08-01
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DOI: https://doi.org/10.52163/yhc.v66iCD12.2948
Issue
Vol. 66 No. CĐ12-NCKH
Section
Articles
How to Cite
Khánh, T. T., Thọ, L. V., Lạc, B. H., & Dũng, L. C. (2025). 24. TUMOUR WIDE RESECTION AND MEGAPROSTHESIS TOTAL KNEE REPLACEMENT FOR DISTAL FEMORAL OSTEOSARCOMA: A CASE REPORT AND LITERATURE REVIEW. Vietnam Journal of Community Medicine, 66(CĐ12-NCKH). https://doi.org/10.52163/yhc.v66iCD12.2948

24. TUMOUR WIDE RESECTION AND MEGAPROSTHESIS TOTAL KNEE REPLACEMENT FOR DISTAL FEMORAL OSTEOSARCOMA: A CASE REPORT AND LITERATURE REVIEW

Tran Tien Khanh1, Le Van Tho1, Bui Hoang Lac1, Le Chi Dung1
1 Hospital for Traumatology and Orthopaedics at Ho Chi Minh city

Main Article Content

Abstract

Objective: To report a case of distal femoral osteosarcoma treated with wide tumor resection and reconstruction using a megaprosthesis total knee replacement, and to evaluate treatment outcomes after six months of follow-up.


Methods: This is a case report of a patient diagnosed with distal femoral osteosarcoma who underwent wide tumor resection and bone defect reconstruction using a megaprosthesis total knee replacement. The patient was followed up at Ho Chi Minh city Orthopaedic and Trauma Hospital from October 2024 to April 2025.


Results: The surgery was successfully performed. At the 6-month follow-up, the patient demonstrated near-complete recovery of knee range of motion (0-130 degrees), with no observable limb length discrepancy. The MSTS functional score was 28, indicating an excellent outcome. No evidence of local recurrence or distant metastasis was detected.


Conclusion: The initial result of this case demonstrates that, in addition to biological reconstruction methods, Megaprosthesis total knee replacement is also an important option in limb-salvage surgery for bone cancer. This approach provides both surgeons and patients with more treatment choices for managing this challenging disease.

Article Details

Keywords

Osteosarcoma, limb salvage surgery, Megaprosthesis knee replacemen.

References

[1] Misaghi A, Goldin A, Awad M, Kulidjian A.A. Osteosarcoma: a comprehensive review. SICOT-J, 2018, 4: 12.
[2] Zhang H.R. Application and development of megaprostheses in limb salvage for bone tumors around the knee joint. Cancer Control, 2022, 29: 1-9.
[3] Palumbo B.T, Henderson E.R, Groundland J.S, Cheong D, Pala E, Letson G.D, Ruggieri P. Advances in segmental endoprosthetic reconstruction for extremity tumors: a review of contemporary designs and techniques. Cancer Control, 2011, 18 (3): 160-7.
[4] Zhang C, Hu J, Zhu K, Cai T, Ma X. Survival, complications and functional outcomes of cemented megaprostheses for high-grade osteosarcoma around the knee. Int Orthop, 2018, 42 (4): 919-29.
[5] Shehadeh A, Noveau J, Malawer M, Henshaw R. Late complications and survival of endoprosthetic reconstruction after resection of bone tumors. Clin Orthop Relat Res, 2010, 468 (11): 2885-95.
[6] Henderson E.R, Groundland J.S, Pala E, Dennis J.A, Wooten R, Cheong D, et al. Failure mode classification for tumor endoprostheses: retrospective review of five institutions and a literature review. J Bone Joint Surg Am, 2011, 93 (5): 418-29.
[7] Myers G.J.C, Abudu A.T, Carter S.R, Tillman R.M, Grimer R.J. Endoprosthetic replacement of the distal femur for bone tumours: long-term results. J Bone Joint Surg Br, 2007, 89 (4): 521-6.
[8] Pala E, Trovarelli G, Angelini A, Ruggieri P. Distal femur reconstruction with modular tumour prostheses: a single institution analysis of implant survival comparing fixed versus rotating hinge knee prostheses. Int Orthop, 2016, 40 (4): 807-16.