Bài báo khoa học Tập 63 Số Số tiếng Anh (2022) 08/12/2022

CLINICAL AND SUBCLINICAL CHARACTERISTICS OF BREAST CANCER PATIENTS UNDERGOING TRASTUZUMAB TREATMENT

Bui Dang Minh Tri1, Ly Cong Duy Anh2, Tong Duc Minh3, Bui Khanh Toan4
1 Pham Ngoc Thach University of Medicine
2 Tay Do University
3 Vietnam Military Medical University
4 Tay Nguyen Institute of Hygiene and Epidemiology
Tác giả liên hệ: drtribui1@gmail.com
DOI: 10.52163/yhc.v63i9.549
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Từ khóa
Breast cancer, trastuzumab, clinical and subclinical features.
Tóm tắt

Objective: Describing the clinical and subclinical characteristics of the breast cancer
patient treated with Trastuzumab at Thong Nhat hospital.
Subjects and methods: A retrospective study on 48 patients with breast cancer were
treated with Trastuzumab at Thong Nhat hospital.
Results: Mean age: 48.4 ± 3.4 years old. The 45-60 age group accounted for the
largest proportion with 47.92%. Functional symptoms: the proportion of patients who
self-examined the tumor accounted for the highest rate with 64.58%. There were
12.50% of patients with pain symptoms, 10.42% of patients with nipple discharge.
Physical symptoms: tumor in the upper-external quadrant accounted for the largest
percentage with 58.33%. The average size of the tumors was 2.78 ± 1.32 (cm). The
main type of lesions was detected on ultrasound was local lesion with over 77.08%
with an unknown boundary feature (66.67%) and invasive, accounting for 43.75%.
Histopathological type accounted for the highest proportion was the invasive tubular
carcinoma (79.92%). Histological degree accounted for the highest percentage was
degree 2 with 45.83%. Stage II accounted for the highest rate with 39.58%, stage VI
had the lowest rate with 10.42%.
Conclusion: Common age of breast cancer patients was 45 - 60 years old, mainly
the self-examined tumor, common breast tumors were found in the upper-external
quadrant. On ultrasound, mainly the local lesion, the boundary was not clear. The
histopathological type was the invasive tubular carcinoma.

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