Articles Vol. 65 No. CĐ 1 - Liên chi hội Phẫu thuật bàn tay 12/03/2024

5. ASSESSMENT OF SERUM VITAMIN D CONCENTRATION ON PATIENTS WITH END STAGE CHRONIC KIDNEY DISEASE WHO ARE ON PERITONEAL DIALYSIS AT THONG NHAT DONG NAI GENERAL HOSPITAL

Thai Pham Thi Hoa1,2, Bui Thi Huyen Thuong1,2, Pham Thi Bao Van1,2
1 Thong Nhat general Hospital of Dong Nai province
2 Bệnh viện Đa khoa Thống Nhất tỉnh Đồng Nai
Corresponding author: drthaihoa72@gmail.com
DOI: 10.52163/yhc.v65iCD1.965
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Keywords
End-stage chronic kidney failure, peritoneal dialysis, vitamin D concentration.
Abstract

Introduction: Peritoneal dialysis is a kidney replacement treatment method that patients perform on their own as an outpatient. Vitamin D plays an important role in human health. Vitamin D deficiency is related to many organs dysfunction in the body such as cognition, immunity, cardiovascular and endocrine systems. Vitamin D deficiency worsens end-stage chronic kidney disease, affects patient survival, and causes a variety of bone disorders, mineral abnormalities, and vascular calcification.

Objectives: This study aims to determine the concentration and prevalence of serum vitamin D deficiency, the relationship between serum vitamin D deficiency and some factors in peritoneal dialysis patients.

Research methods: Cross-sectional descriptive study.

Results: The average Vitamin D concentration in peritoneal dialysis patients was 20.29 ± 7.98 ng/ml, the lowest was 1.69 ng/ml and the highest was 47.17 ng/ml. The prevalence of vitamin D deficiency was 94.59%. Vitamin D and blood albumin levels are positively correlated (r = 0.48 and p < 0.001). There is a negative correlation between vitamin D concentration and blood PTH (r = - 0.25 and p < 0.05). There is no relationship between vitamin D concentration and age, BMI, peritoneal dialysis time, Hb, Calcium, phosphorus and blood protein.

Conclusion: The prevalence of vitamin D deficiency in peritoneal dialysis patients is very high, most patients with vitamin D deficiency have muscle pain and cramps. Low serum albumin and high serum PTH concentration are associated with vitamin D deficiency.

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