Articles Vol. 65 No. 2 08/03/2024

20. CLINICAL AND SUBCLINICAL FEATURES OF NON-ALCOHOLIC FATTY LIVER DISEASE (NAFD) IN PATIENT WITH TYPE 2 DIABETES MELLITUS IN NGHE AN FRIENDSHIP GENERAL HOSPITAL 2023

Le Thi Hoa1,2, Nguyen Cong Long3,4, Ngo Tri Hiep5,6, Le Thi Hue1,2
1 Nghe An General Friendship Hospital
2 Bệnh viện Hữu nghị đa khoa Nghệ An
3 Bach Mai Hospital
4 Bệnh viện Bạch Mai
5 Vinh Medical University
6 Đại học Y khoa Vinh
Corresponding author: ngocdiepmiss1403@gmail.com
DOI: 10.52163/yhc.v65i2.939
17 Views
16 Downloads
Abstract

Objectives: To investigate non-alcoholic fatty liver disease’s clinical and subclinical characteristics in patients with type 2 diabetes from July 2022 to June 2023.

Population and methods: Case series description of 262 patients who had type 2 diabetes with nonalcoholic fatty liver disease. Diagnosis of fatty liver by ultrasound.

Results: Average age 66.5 ± 10.7; the ratio of men and women is 49.2% and 50.8%. Typical clinical symptoms are fatigue and loss of appetite (99.6% and 96.6%). Common paraclinical indicators include decreased red blood cell count, decreased hemoglobin, increased LDL-C, and increased HDL-C in 34.4%, 75.9%, 71.0%, and 38.9%, respectively. Hemoglobin count, platelet count, and LDL-C index in women were higher than in men, with p<0.05. The degree of fatty liver on ultrasound is mainly

Conclusion: Non-alcoholic fatty liver disease in patients with type 2 diabetes has unclear clinical features, and subclinical characteristics differ between men and women.

References
[1]
Asia Muhammad N, Non-Alcoholic Fatty Liver Google Scholar
[2]
Disease, an Overview. Integr Med (Encinitas), Google Scholar
[3]
(2), 2019,42-49. Google Scholar
[4]
Quentin MA, Helen LR, Elena K et al., From Google Scholar
[5]
NASH to HCC: current concepts and future Google Scholar
[6]
challenges, Nat Rev Gastroenterol Hepatol, Google Scholar
[7]
(7), 2019, 411-428. Google Scholar
[8]
Byung Wan Lee YHL, Cheol YP et al., Google Scholar
[9]
NonAlcoholic Fatty Liver Disease in Patients with Google Scholar
[10]
Type 2 Diabetes Mellitus: A Position Statement Google Scholar
[11]
of the Fatty Liver Research Group of the Korean Google Scholar
[12]
Diabetes Association, Diabetes Metab J, 44(3), Google Scholar
[13]
, 382-401. Google Scholar
[14]
Singal AK, Anand BS, Recent Trends in the Google Scholar
[15]
Epidemiology of Alcoholic Liver Disease, Google Scholar
[16]
Clinical Liver Disease, 2(2), 2013, 53-56. Google Scholar
[17]
Trần Thị Khánh Tường, Yếu tố nguy cơ dự đoán Google Scholar
[18]
xơ hóa gan tiến triển trên bệnh nhân đái tháo Google Scholar
[19]
đường type 2 bị bệnh gan nhiễm mỡ không do Google Scholar
[20]
rượu, Tạp chí Y dược lâm sàng 108, 15(4), 2020, Google Scholar
[22]
Chongyang Ma KY, Zisong W et al., The Google Scholar
[23]
association between hypertension and Google Scholar
[24]
nonalcoholic fatty liver disease (NAFLD): Google Scholar
[25]
literature evidence and systems biology analysis, Google Scholar
[26]
Bioengineered, 12(1), 2021, 2187-2202.159 Google Scholar
[27]
Phan Diễm Quỳnh, Đỗ Trung Quân, Nhận xét Google Scholar
[28]
tình trạng đề kháng insulin trên bệnh nhân gan Google Scholar
[29]
nhiễm mỡ, Tạp chí nội tiết Đái tháo đường, 41, Google Scholar
[30]
, 106-117. Google Scholar
[31]
O Akha, al HFe. Evaluation of the Correlation Google Scholar
[32]
between Non-Alcoholic Fatty Liver Disease and Google Scholar
[33]
Insulin Resistance, Iranian Red Crescent Medical Google Scholar
[34]
Journal, 12(3), 2010, 282-286. Google Scholar
[35]
Ferraioli G, Soares Monteiro LB, Ultrasoundbased Google Scholar
[36]
techniques for the diagnosis of liver steatosis. Google Scholar
[37]
World J Gastroenterol; 25(40), 2019,6053-6062. Google Scholar
[38]
Muzica CM, Sfarti C, Trifan A et al., Google Scholar
[39]
Nonalcoholic Fatty Liver Disease and Type 2 Google Scholar
[40]
Diabetes Mellitus: A Bidirectional Relationship, Google Scholar
[41]
Can J Gastroenterol Hepatol, 2020:6638306. Google Scholar