Articles Vol. 65 No. 2 08/03/2024

7. MULTIMORBIDITY BURDEN AND ITS ASSOCIATION WITH FRAILTY IN OSTEOPOROTIC OLDER ADULTS

Truong Tri Khoa1,2, Nguyen Thanh Huan1,2, Nguyen Duc Cong3,4
1 University of Medicine and Pharmacy at Ho Chi Minh city
2 Đại học Y Dược TP. Hồ Chí Minh
3 Pham Ngoc Thach University of Medicine
4 Đại học Y khoa Phạm Ngọc Thạch
Corresponding author: cardiohuan@gmail.com
DOI: 10.52163/yhc.v65i2.924
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Keywords
Multimorbidity, frailty, osteoporosis, older adults.
Abstract

Objective: To evaluate the prevalence of multimorbidity and the association between multimorbidity and frailty in older adults with osteoporosis.

Method: A cross-sectional descriptive study was conducted on 296 older adults treated at the Department of Rheumatology, the Department of Neurosurgery, Rheumatology clinic, University Medical Center Ho Chi Minh city.

Results: The prevalence of multimorbidity among participants was 43,2% (128/296). The common comorbidities included osteoarthritis and hypertension. The multimorbidity group was more likely to have higher mean age, history of vertebral fracture, ADL and IADL dependence, and frailty than the non-multimorbidity group. However, the multimorbidity group was less likely to be physically active than the other group. In the univariate logistic regression model, multimorbidity was associated with frailty, but the association was insignificant when the regression models were adjusted for age.

Conclusion: Older adults with osteoporosis had a relatively high multimorbidity burden of 43,2%. Multimorbidity was associated with frailty in the univariate model but this association did not persist when the models were adjusted for age.

References
[1]
Salive ME, Multimorbidity in older adults. Google Scholar
[2]
Epidemiol Rev, 35, 2013, 75-83. Google Scholar
[3]
Rizzuto D, Melis RJF, Angleman S et al., Effect Google Scholar
[4]
of Chronic Diseases and Multimorbidity on Google Scholar
[5]
Survival and Functioning in Elderly Adults. J Google Scholar
[6]
Am Geriatr Soc, 65(5), 2017, 1056-60. Google Scholar
[7]
Bliuc D, Tran T, Chen W et al., The association Google Scholar
[8]
between multimorbidity and osteoporosis Google Scholar
[9]
investigation and treatment in high-risk fracture Google Scholar
[10]
patients in Australia: A prospective cohort study. Google Scholar
[11]
PLoS Med, 20(1), 2023, e1004142. Google Scholar
[12]
Luo Y, Chen Y, Wang K et al., Associations Google Scholar
[13]
between multimorbidity and frailty transitions Google Scholar
[14]
among older Americans, J Cachexia Sarcopenia Google Scholar
[15]
Muscle, 14(2), 2023, 1075-82. Google Scholar
[16]
Chen Y, Shi L, Zheng X et al., Patterns and Google Scholar
[17]
Determinants of Multimorbidity in Older Adults: Google Scholar
[18]
Study in Health-Ecological Perspective. Int J Google Scholar
[19]
Environ Res Public Health, 19(24), 2022. Google Scholar
[20]
Barcelos A, Lopes DG, Canhao H et al., Google Scholar
[21]
Multimorbidity is associated with fragility Google Scholar
[22]
fractures in women 50 years and older: A Google Scholar
[23]
nationwide cross-sectional study. Bone Google Scholar
[24]
Rep,15:101139, 2021. Google Scholar
[25]
Rodrigues LP, de Oliveira Rezende AT, Google Scholar
[26]
Delpino FM et al., Association between Google Scholar
[27]
multimorbidity and hospitalization in older Google Scholar
[28]
adults: systematic review and meta-analysis. Google Scholar
[29]
Age Ageing, 51(7), 2022. Google Scholar
[30]
Gao C, Xu Y, Li L et al., Prevalence of Google Scholar
[31]
osteoporotic vertebral fracture among Google Scholar
[32]
community-dwelling elderly in Shanghai. Chin Google Scholar
[33]
Med J (Engl), 132(14):1749-51, 2019. Google Scholar
[34]
Christofoletti M, Sandreschi PF, Quadros EN Google Scholar
[35]
et al., Physical activity and sedentary behavior Google Scholar
[36]
as multimorbidity discriminators among elderly Google Scholar
[37]
Brazilians: a cross-sectional study. Sao Paulo Google Scholar
[38]
Med J, 139(4):372-9, 2021. Google Scholar
[39]
Vetrano DL, Palmer K, Marengoni A et al., Google Scholar
[40]
Frailty and Multimorbidity: A Systematic Google Scholar
[41]
Review and Meta-analysis. J Gerontol A Biol Sci Google Scholar
[42]
Med Sci, 74(5):659-66, 2019. Google Scholar