Objectives: Procalcitonin was rated highest on all three criteria of diagnosis, prognosis and infection monitoring.
Research objective: To evaluate the diagnostic and prognostic value of procalcitonin in patients with septic shock.
Subjects and Methods: Cross-sectional descriptive study with analysis of 92 patients diagnosed with septic shock were admitted to the ICU department from July to October 2022.
Results: At the time of septic shock, the serum procalcitonin concentration was greater than 10ng/ ml, the mean procalcitonin in the mortality group was higher than the survival group (p<0.05). The diagnostic value of procalcitonin for septic shock with AUC = 0.717 (95% CI), at the procalcitonin threshold of 46 ng/mL, has a sensitivity of 77.27% and a specificity of 70%. Procalcitonin was positively correlated with SOFA (r=0.44, p<0.01) and APACHE II score (r=0.479, p<0.01). The best predictability of mortality with the area under the ROC curve was 0.896, sensitivity 87.5%, and specificity 81.3% at 48 hours after septic shock.
Conclusions: Procalcitonin is a valuable marker in diagnosis and prognosis of septic shock.