Articles Vol. 65 No. 1 18/01/2024

9. SURGICAL TREATMENT OF PERIPHERAL TUBERCULOSIS IN NATIONAL LUNG HOSPITAL

Nguyen Xuan Dien1,2, Dam Toa1,2
1 National Lung Hospital
2 Bệnh viện Phổi Trung ương
Corresponding author: chirnguyenxuandien@gmail.com
DOI: 10.52163/yhc.v65i1.882
27 Views
31 Downloads
Abstract

Background: Peripheral lymphadenopathy is the most common disease in extrapulmonary TB diseases, TB bacteria follow the lymph node route to the lymph nodes, causing lymphadenitis, swollen lymphadenopathy, persistent lymphadenopathy. Diagnosing peripheral lymphadenopathy is difficult, especially requiring evidence of TB bacteria. The surgical treatment resolves the complication of lymph node abscess, avoids scars, bad shrinkage, heavy aesthetic effects.

Objectives: Evaluate the role and results of surgery in the treatment of peripheral lymph node tuberculosis.

Subjects and methods: A cross-sectional descriptive study of 105 patients with tuberculosis of the peripheral lymph nodes from June 1, 2020, to June 30, 2021, who underwent surgical curettage to clear inflammation and remove pus., take tissue necrosis and test LPA, MGIT (bactec), histopathology. All patients were treated with TB drugs according to the National TB Program's regimen of 12 months (2RHZE/10RHE), wound healing time after surgery and detection of drug resistance.

Results: 105 patients, 67 women, 38 men, mean age 32.26 ± 12.1; cervical lymph node location 97/105 (92.4%), right neck more than left neck (58 and 36), 77 patients with purulent necrotizing lymphadenitis, 28 patients with biopsy results of tuberculosis, tuberculosis inflamed tissue 97 (92.4%), LPA 25/105 (23/8%), MGIT 59/105 (56.2%) was positive. Multidrug resistance has four patients with rifampicin (4/59); The most resistant drugs are Streptomycin and Isoniazid. Conclusion: Surgical treatment of peripheral lymph node TB achieves 2 goals: resolving complications of lymph node TB and taking specimens for testing to detect drug resistance

References
[1]
Subrahmanyam M, Role of surgery and Google Scholar
[2]
chemotherapy for peripheral lymph node Google Scholar
[3]
tuberculosis, Br J Surg; 80(12), 1993, pp. 1547-8 Google Scholar
[4]
Campbell IA, Dyson AJ, Lymph node Google Scholar
[5]
tuberculosis: a comparison of various methods Google Scholar
[6]
of treatment, Tubercle; 58(4), 1977, pp. 171-9 Google Scholar
[7]
Lekhbal A et al., Treatment of cervical lymph Google Scholar
[8]
node tuberculosis: When surgery should be Google Scholar
[9]
performed? A retrospective cohort study, Ann Google Scholar
[10]
Med Surg (Lond); 55, 2020, pp. 159-163 Google Scholar
[11]
Jawahar MS, Scrofula revisited: an update on Google Scholar
[12]
the diagnosis and management of tuberculosis of Google Scholar
[13]
superficial lymph nodes", Indian J Pediatr; 67(2 Google Scholar
[14]
Suppl), 2000, pp. S28-33 Google Scholar
[15]
Jawahar MS et al., Treatment of lymph node Google Scholar
[16]
tuberculosis--a randomized clinical trial of two Google Scholar
[17]
-month regimens, Trop Med Int Health. 10(11), Google Scholar
[18]
, pp. 1090-8 Google Scholar
[19]
Li Q et al., Clinical analysis of lateral cervical Google Scholar
[20]
approach in the treatment of cervical lymphatic Google Scholar
[21]
tuberculosis complicated with parapharyngeal Google Scholar
[22]
space abscess, Lin Chung Er Bi Yan Hou Tou Google Scholar
[23]
Jing Wai Ke Za Zhi. 35(7), 2021, pp. 593-598 Google Scholar
[24]
Mihashi H et al., A clinical study on cervical Google Scholar
[25]
tuberculous lymphadenitis: the position of a Google Scholar
[26]
low invasive needle aspiration procedure for the Google Scholar
[27]
diagnosis of cervical tuberculous lymphadenitis, Google Scholar
[28]
Nihon Jibiinkoka Gakkai Kaiho; 115(12), 2012, Google Scholar
[29]
pp. 1037-42 Google Scholar
[30]
Polesky A, Grove W, Bhatia G., Peripheral Google Scholar
[31]
tuberculous lymphadenitis: epidemiology, Google Scholar
[32]
diagnosis, treatment, and outcome, Medicine Google Scholar
[33]
(Baltimore). 84(6), 2005, pp. 350-362 Google Scholar
[34]
Chahed H et al., Paradoxical reaction associated Google Scholar
[35]
with cervical lymph node tuberculosis: predictive Google Scholar
[36]
factors and therapeutic management, Int J Infect Google Scholar
[37]
Dis. 54, 2017, pp. 4-7 Google Scholar