Articles Vol. 64 No. 5 23/08/2023

34. SAFETY OF USING SINGLE-NUCLEAR CELL CONTAINING STEM CELLS FROM THE AUTOLOGOUS BONE MARROW IN TREATING CHILDREN WITH CEREBRAL PALSY DUE TO ASPHYXIA IN VINMEC TIMES CITY HOSPITAL

Vu Duy Chinh1,2, Nguyen Thanh Liem3,4, Nguyen Trung Kien3,4
1 Vinmec International General Hospital
2 Bệnh viện Vinmec Times City
3 Vinmec Institute of Stem cell and Gene Technology
4 Viện Nghiên cứu tế bào gốc và công nghệ gen Vinmec
Corresponding author: vdchinh.vn@gmail.com
DOI: 10.52163/yhc.v64i5.791
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Keywords
Stemcell, cerebral palsy.
Abstract

Objective: Research using single -nuclear cell containing stem cells from autologous bone marrow in treating children with cerebral palsy due to brain hypoxia at birth was accepted at the Ministry of Science and Technology in September 2018. Initial results showed safety and evidence of effectiveness. The objective of this study is to confirm the safety of a single -nuclear cell containing stem cells from autologous bone marrow on a larger sample size in children with cerebral palsy due to asphyxia at birth.

Subjects and methods: This is a restrospective-perspective combined conducted in more than 50 cerebral palsy patients due to asphyxia that has been infused the single cell containing stem cells from the autologous bone marrow at Vinmec International Hospital. The Safety was assessed during the first and second transfusion and throughout the 12-month study period.

Results: There were no serious adverse events identified as associated with transfusion of single -nuclear cell containing stem cells from autologous bone marrow in treating children with cerebral palsy due to brain hypoxia.

Conclusion: Using single -nuclear cell masses containing stem cells from the autologous bone marrow in the treatment of children with cerebral palsy due to asphyxia is safe.

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