Articles Vol. 64 No. 5 23/08/2023

8. EVALUATION OF TREATMENT RESULTS OF SUDDEN DEAFNESS USING HYPERBARIC OXYGEN THERAPY

Quan Thanh Nam1,2, Nghiem Duc Thuan1,2, Vu Van Minh1,2, Mai Van Tuan3,4, Le Thi Hoai Thu3,4
1 Military Hospial 103
2 Bệnh viện Quân y 103
3 Military Hospial 354
4 Bệnh viện Quân y 354
Corresponding author: dr.namb6@gmail.com
DOI: 10.52163/yhc.v64i5.764
24 Views
17 Downloads
Keywords
Sudden deafness, sudden sensorineural hearing loss, hyperbaric oxygen.
Abstract

Objective: This study aims to evaluate the treatment results of sudden deafness (SD) using hyperbaric oxygen therapy (HBOT).

Subjects and methods: Prospective interventional study, comparing pre- and post-treatment results.

Results: The study included participants with a mean age of 54.9 ± 15.1 years and a male-to-female ratio of 1.32. Among the patients, 43.1% did not report any factors associated with the disease. The majority of patients sought treatment within 7 days (64.6%). All patients (100%) presented with symptoms of hearing loss and tinnitus, and 95.1% experienced a feeling of fullness in the ear. The rising audiogram pattern was observed in 52.3% of cases. The cases with mild hearing loss represented the most prevalent proportion at admission (76.8%). After treatment, most patients achieved a normal pure-tone audiometry (PTA) result (63.8%); with only 1 patient classified as having moderate hearing loss. 50.7% of patients demonstrated complete improvement, while 14.5% showed partial improvement based on Siegel’s criteria. The HBOT-treated group exhibited a significantly greater improvement in PTA (18.9 ± 8.6dB) compared to the non-HBOT-treated group (12.9 ± 5.0dB) (p <0.05).

Conclusion: Sudden deafness patients treated with HBOT exhibited better hearing recovery results than those treated with conventional medical interventions.

References
[1]
Chandrasekhar SS, Do BT, Schwartz SR et al., Google Scholar
[2]
“Clinical practice guideline: sudden hearing Google Scholar
[3]
loss (update)”, Otolaryngology - Head and Neck Google Scholar
[4]
Surgery, 161(1_suppl): S1 - S45, 2019. Google Scholar
[5]
Ngô Ngọc Liễn, “Mức độ nghe kém”, Giản yếu Google Scholar
[6]
Tai Mũi Họng, tập1, tr. 197 – 201, 1996. Google Scholar
[7]
Choung YH, Park K, Shin YR et al., Google Scholar
[8]
“Intratympanic dexamethasone injection for Google Scholar
[9]
refractory sudden sensorineural hearing loss”, Google Scholar
[10]
The Laryngoscope, 116(5):747 – 752, 2006. Google Scholar
[11]
Filipo R, Attanasio G, Viccaro M et al., Google Scholar
[12]
“Hyperbaric oxygen therapy with short duration Google Scholar
[13]
intratympanic steroid therapy for sudden hearing Google Scholar
[14]
loss” Acta Otolaryngol, 132:475-81, 2012. Google Scholar
[15]
Cheng YF, Chu YC, Tu TY et al., “Modified Google Scholar
[16]
Siegel’s criteria for sudden sensorineural hearing Google Scholar
[17]
loss: Reporting recovery outcomes with matched Google Scholar
[18]
pretreatment hearing grades”, J Journal of the Google Scholar
[19]
Chinese Medical Association, 81(11): 1008 – Google Scholar
[20]
, 2018. Google Scholar
[21]
Battista RA, “Intratympanic dexamethasone Google Scholar
[22]
for profound idiopathic sudden sensorineural Google Scholar
[23]
hearing loss”, Otolaryngology - Head and Neck Google Scholar
[24]
Surgery, 132(6): 902 – 905, 2005. Google Scholar
[25]
Covelli E, Altabaa K, Verillaudet B et al., Google Scholar
[26]
“Intratympanic steroids as a salvage therapy Google Scholar
[27]
for severe to profound idiopathic sudden Google Scholar
[28]
sensorineural hearing loss”, Acta oto – Google Scholar
[29]
laryngologica, 138(11): 966 – 971, 2018. Google Scholar
[30]
Liu CS, Kang HB, Lee JC et al., “Comparison Google Scholar
[31]
of therapeutic results in sudden sensorineural Google Scholar
[32]
hearing loss with/without additional hyperbaric Google Scholar
[33]
oxygen therapy: a retrospective review of Google Scholar
[34]
audiologically controlled cases”, Clinical Google Scholar
[35]
Otolaryngology, 36(2): 121 – 128, 2011. Google Scholar
[36]
Filipo R, Attanasio G, Viccaro M et al., Google Scholar
[37]
“Hyperbaric oxygentherapy with short duration Google Scholar
[38]
intratympanic steroid therapy forsudden hearing Google Scholar
[39]
loss”. Acta Otolaryngol, 132:475–48, 2012. Google Scholar
[40]
Eryigit B, Ziylan F, Yaz F et al., “The Google Scholar
[41]
effectiveness of hyperbaric oxygen in patients Google Scholar
[42]
with idiopathic sudden senso-rineural hearing Google Scholar
[43]
loss: a systematic review”. Eur Arch Oto-RhinoLaryngol, Google Scholar
[44]
(12):2893–290, 2018. Google Scholar