Articles Vol. 64 No. CD 5 -Nghiên cứu khoa học 24/07/2024

QUALITY OF LIFE IN THALASSEMIA PATIENTS WITH IRON OVERLOAD AT THE NATIONAL INSTITUTE OF HEMATOLOGY AND BLOOD TRANSFUSION IN 2022

Nguyen Thi Dinh1,2, Tran Ngoc Que3,4, Pham Thi Hoa3,4, Tong Quang Manh3,4, Nguyen Thi Tuyen3,4, Hoang Phuong Linh3,4, Nguyen Cong Khan1,2
1 Thang Long University
2 Trường Đại học Thăng Long
3 National Institute of Hematology and Blood Transfusion
4 Viện Huyết học - Truyền máu Trung ương
Corresponding author: nguyenthidinh10061983@gmail.com
DOI: 10.52163/yhc.v64i4.711
18 Views
0 Downloads
Keywords
Quality of life (QoL); SF-36; physical health, mental health.
Abstract

Objectives: Describe the quality of life of Thalassemia patients with iron overload at the National
Institute of Hematology and Blood Transfusion.
Methods: cross-sectional descriptive study was conducted on 388 patients treated at the National
Institute of Hematology and Blood Transfusion.
Results: PCS 38.9±18.4; MCS 40.2±19.7; HRQoL score 39.6±17.2. HRQoL in men (46.5±16,8)
higher than in women (37.5±15,7); urban (46.2±16.8) higher than in rural mountainous (39.2±17.2);
patients with moderate iron overload (42.7±17.4) was higher than the severe (38.2±19.2).
Conclusion: The patient’s quality of life was low with 39.4% poor and 60.6% moderate or higher.
Quality of life varies by age, gender, place of residence, iron overload status and duration of treatment.

References
[1]
Weatherall DJ, The inherited diseases of Google Scholar
[2]
hemoglobin are an emerging global health burden. Google Scholar
[3]
Blood. 2010 Jun 3;115(22):4331–6. http:// Google Scholar
[4]
dx.doi.org/10.1182/blood-2010-01-251348 Google Scholar
[5]
PMID:20233970 Google Scholar
[6]
Nguyễn Thị Thu Hà, Bạch Quốc Khánh, Tổng Google Scholar
[7]
quan Thalassemia, thực trạng, nguy cơ và giải Google Scholar
[8]
pháp kiểm soát bệnh Thalassemia tại Việt Nam, Google Scholar
[9]
Tạp chí Y học Việt Nam, tập 502 – tháng 5, số Google Scholar
[10]
chuyên đề 2021. Google Scholar
[11]
WHO, Rand Health Medical Outcomes Study: Google Scholar
[12]
-Item Short Form Survey Scoring Instructions. Google Scholar
[13]
Access to https://www.rand.org/health-care/ Google Scholar
[14]
surveys_tools/mos/36-item-short-form/scoring. Google Scholar
[15]
html, 2005 Google Scholar
[16]
Adam S, Quality of life outcomes in thalassemia Google Scholar
[17]
patients in Saudi Arabia: a cross-sectional study. Google Scholar
[18]
East Mediterr Health J, 25(12): pp.887–895 Google Scholar
[19]
https://doi.org/10.26719/2019.25.12.887, 2019. Google Scholar
[20]
Nguyễn Xuân Thái, Chất lượng cuộc sống của Google Scholar
[21]
bệnh nhân thalassemia điều trị tại Viện Huyết Google Scholar
[22]
học – Truyền máu Trung ương năm 2016 và một Google Scholar
[23]
số yếu tố liên quan, Luận văn thạc sỹ y tế công Google Scholar
[24]
cộng, Trường đại học Y tế công cộng, 2017. Google Scholar
[25]
Mahdieh A, Majid M et al., Health-related Google Scholar
[26]
quality of life (HRQoL) in beta-thalassemia Google Scholar
[27]
major (β-TM) patients assessed by 36-item short Google Scholar
[28]
form health survey (SF-36): a meta-analysis. Google Scholar
[29]
Qual Life Res, 28(2), pp.321-334. https://doi. Google Scholar
[30]
org/10.1007/s11136-018-1986-1, 2019 Google Scholar
[31]
Mojtaba MSB, Elham MN, A Comparison of Google Scholar
[32]
Quality of Life between Adolescences with Google Scholar
[33]
Beta Thalassemia Major and their Healthy Google Scholar
[34]
Peers. International Journal of Pediatrics, 4(1), Google Scholar
[35]
pp.1195-1204, 2016. Google Scholar
[36]
Maria DC, Antonis K et al., Quality of Life Google Scholar
[37]
in Patients with β-Thalassemia: Transfusion Google Scholar
[38]
Dependent Versus Non-Transfusion Dependent. Google Scholar
[39]
Blood, Volume 130, (S1), pp.751 – 753, 2017. Google Scholar
[40]
Amid A, Saliba AN, Taher AT et al., Thalassaemia Google Scholar
[41]
in children: from quality of care to quality of life. Google Scholar
[42]
Arch Dis Child, 100(11), pp.1051–1057, 2015. Google Scholar