Articles Tập 67 Số CĐ16 05/11/2026

IN-HOSPITAL GLYCEMIC CONTROL AND MORTALITY AMONG PATIENTS WITH COVID-19 AND TYPE 2 DIABETES AT THE HOSPITAL FOR TROPICAL DISEASES, HO CHI MINH CITY, 2021-2022

Huynh Thi Thuy Anh, Le Buu Chau, Le Thi Diem
DOI: 10.52163/yhc.v67iCD16.6990
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Abstract

Objective: To describe in-hospital blood glucose levels and their association with mortality among patients with COVID-19 and type 2 diabetes.

Subjects and methods: A retrospective descriptive-analytical study was conducted on 154 patients with COVID-19 and type 2 diabetes hospitalized at Hospital for Tropical Diseases, Ho Chi Minh city from June 2021 to September 2022.

Results: Among 154 patients, 31 died, accounting for 20.1%. The mean blood glucose level at admission was 243 ± 152 mg/dL, and the mean in-hospital blood glucose level was 223 ± 55 mg/dL. A total of 121 patients had mean in-hospital blood glucose > 180 mg/dL, accounting for 78.6%. Non-survivors had higher mean in-hospital blood glucose than survivors, 244 ± 47 mg/dL versus 217 ± 55 mg/dL; p = 0.015. Mean in-hospital blood glucose > 180 mg/dL was observed in 30/31 non-survivors and 91/123 survivors and was associated with mortality in univariable analysis, with OR = 10.55; 95% CI: 1.38-80.54; p = 0.006.

Conclusion: Mean in-hospital blood glucose > 180 mg/dL was common among patients with COVID-19 and type 2 diabetes and was associated with mortality in univariable analysis. Close blood glucose monitoring is needed in this patient group during treatment.

Keywords
COVID-19, type 2 diabetes, in-hospital blood glucose, mortality
References
[1]
[1] Guo W, Li M, Dong Y, Zhou H, Zhang Z, Tian C et al. Diabetes is a risk factor for the progression and prognosis of COVID-19. Diabetes Metab Res Rev, 2020, 36 (7): e3319. doi: 10.1002/dmrr.3319. Google Scholar
[2]
[2] Huang I, Lim M.A, Pranata R. Diabetes mellitus is associated with increased mortality and severity of disease in COVID-19 pneumonia: a systematic review, meta-analysis, and meta-regression. Diabetes Metab Syndr, 2020, 14 (4): 395-403. doi: 10.1016/j.dsx.2020.04.018. Google Scholar
[3]
[3] Bode B, Garrett V, Messler J, McFarland R, Crowe J, Booth R et al. Glycemic characteristics and clinical outcomes of COVID-19 patients hospitalized in the United States. J Diabetes Sci Technol, 2020, 14 (4): 813-821. doi: 10.1177/1932296820924469. Google Scholar
[4]
[4] Korytkowski M.T, Muniyappa R, Antinori-Lent K, Donihi A.C, Drincic A.T, Hirsch I.B et al. Management of hyperglycemia in hospitalized adult patients in non-critical care settings: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab, 2022, 107 (8): 2101-2128. doi: 10.1210/clinem/dgac278. Google Scholar
[5]
[5] Huynh T.T.A, Le B.C, Nguyen B.A.H, Tran T.T, Nguyen K, Van P.T et al. Clinical characteristics and outcomes of hospitalized patients with COVID-19 and type 2 diabetes in Vietnam: a retrospective study. Cureus, 2026, 18 (4): e108011. doi: 10.7759/cureus.108011. Google Scholar
[6]
[6] American Diabetes Association. Classification and diagnosis of diabetes: standards of medical care in diabetes-2021. Diabetes Care, 2021, 44 (Suppl 1): S15-S33. doi: 10.2337/dc21-S002. Google Scholar
[7]
[7] Bộ Y tế. Quyết định số 2671/QĐ-BYT, ngày 26 tháng 6 năm 2023, về việc ban hành Hướng dẫn chẩn đoán và điều trị COVID-19. Google Scholar
[8]
[8] Ranieri V.M, Rubenfeld G.D, Thompson B.T, Ferguson N.D, Caldwell E, Fan E et al. Acute respiratory distress syndrome: the Berlin definition. JAMA, 2012, 307 (23): 2526-2533. doi: 10.1001/jama.2012.5669. Google Scholar
[9]
[9] Palevsky P.M, Liu K.D, Brophy P.D, Chawla L.S, Parikh C.R, Thakar C.V et al. KDOQI US commentary on the 2012 KDIGO clinical practice guideline for acute kidney injury. Am J Kidney Dis, 2013, 61 (5): 649-672. doi: 10.1053/j.ajkd.2013.02.349. Google Scholar