Articles Tập 67 Số CĐ16 02/11/2026

ASSOCIATION BETWEEN INFECTION AND NUTRITIONAL STATUS IN PATIENTS UNDERGOING SURGERY FOR SEVERE TRAUMATIC BRAIN INJURY AT 108 MILITARY CENTRAL HOSPITAL

Nguyen The Vinh, Le Dinh Toan, Nguyen Cong Thanh, Nguyen Duy Tuan, Tran Thi Thanh, Phan Thi Thu Thao, Dang Tien Dung, Tran Lan Huong, Nguyen Thi Hong Tham
DOI: 10.52163/yhc.v67iCD16.6935
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Abstract

Objective: To analyze the association between infection status and nutritional status among patients undergoing surgery for severe traumatic brain injury at 108 Military Central Hospital.

Subjects and methods: A prospective descriptive analytical study was conducted among 67 patients aged 18 years or older with severe traumatic brain injury (Glasgow Coma Scale score ≤ 8) who underwent neurosurgery and were treated in the Neurocritical Care Unit of 108 Military Central Hospital from February to October 2025. Infection status was assessed according to the CDC/NHSN criteria. Nutritional status was evaluated using body mass index (BMI), mid-upper arm circumference (MUAC), fat body mass (FBM), lean body mass (LBM), subjective global assessment (SGA), and the modified nutrition risk in the critically ill (mNUTRIC) score on postoperative days 1, 7, and 14. Data were analyzed using SPSS version 20.0, with Pearson’s correlation coefficient and the independent-samples t-test.

Results: Nutritional indicators showed a gradual decline during the first 14 postoperative days. Correlations between inflammatory markers, including white blood cell count, procalcitonin, and C-reactive protein, and nutritional indicators were weak, with correlation coefficients ranging from -0.274 to 0.294. Patients with infection had significantly higher FBM than those without infection on postoperative days 1 and 7 (p = 0.011), whereas no significant differences were observed in BMI, MUAC, LBM, or SGA (p > 0.05). On postoperative day 7, patients with CRP levels ≥ 100 mg/L had significantly higher mNUTRIC scores than those with CRP levels < 100 mg/L (3.50 ± 1.57 vs. 2.56 ± 1.44; p = 0.014).

Conclusion: The associations between inflammatory markers and nutritional indicators among patients undergoing surgery for severe traumatic brain injury were generally weak. Patients with infection had higher fat body mass during the early postoperative period, while severe inflammation, defined as CRP ≥ 100 mg/L, was associated with a higher nutritional risk according to the mNUTRIC score.

Keywords
Severe traumatic brain injury, association, infection, nutritional status.
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