Objectives: To describe the clinical and subclinical characteristics and treatment outcomes of pediatric patients (aged 6–15 years) diagnosed with UGIB due to peptic ulcer disease at Can Tho Children's Hospital from May 2024 to May 2026.
Subjects and methods: A prospective descriptive cohort study was conducted on 60 children diagnosed with UGIB secondary to peptic ulcer disease who met the inclusion and exclusion criteria at Can Tho Children's Hospital to May 2024 and May 2026. Eligible patients were consecutively enrolled throughout the study period. Data were collected prospectively using standardized case report forms from the time of hospital admission and patients were followed until hospital discharge.
Results: The mean age was 12.2 ± 2.5 years, and 76.7% of the patients were male. Melena was the most common reason for hospital admission (30%). Abdominal pain was the most common gastrointestinal symptom, occurring in 80% of the pediatric patients. Most cases of upper gastrointestinal bleeding were classified as mild (80%). Upper gastrointestinal endoscopy revealed that duodenal ulcers were the predominant lesions (96.7%); most ulcers were small (<1 cm, 65%) and solitary (70%). According to the Forrest classification, Forrest III ulcers accounted for the highest proportion (95%). The prevalence of confirmed Helicobacter pylori infection was 91.7%. Medical management was provided for 96.7% of the patients, all patients were discharged from the hospital, and no deaths were recorded.
Conclusion: Upper gastrointestinal bleeding secondary to peptic ulcer disease occurred predominantly in boys. Most cases of upper gastrointestinal bleeding were classified as mild.