Objective: To determine the antibiotic resistance status of Klebsiella pneumoniae isolated at Dien Bien provincial General Hospital in 2024.
Methods: A cross-sectional study was conducted to analyse the distribution and antibiotic resistance profiles of the isolated K.pneumoniae strains.
Results: Among the 99 isolated K.pneumoniae strains, 62.6% were isolated from male patients, and patients over 60 years old accounted for 60.6% of cases. Most isolates were obtained from respiratory samples (82.8%), predominantly from patients in the ICU and Emergency Departments (41.4%). The bacteria showed resistance to multiple antibiotics, including Ampicillin (99%), Amoxicillin/Clavulanic acid (52%), Cefotaxime (57.1%), Cefazolin (60.2%), Ceftazidime (48%), Imipenem (46.9%), Trimethoprim/Sulfamethoxazole (58.2%), and Ciprofloxacin (66.3%). Notably, K.pneumoniae demonstrated complete susceptibility to Cefepime (100%), followed by Amikacin (81.6%), Meropenem (69.4%), and Ertapenem (68.4%).
Conclusion: K.pneumoniae infections were most prevalent among the elderly and patients treated in the ICU and Emergency Department, with respiratory tract specimens being the predominant source of isolates. The bacteria exhibited multi-drug resistance, including resistance to both Carbapenem s and 3rd-generation Cephalosporins. Cefepime and Amikacin remain potentially effective options for treating infections caused by K.pneumoniae.