Objective: To evaluate the preliminary clinical outcomes of single-incision full-endoscopic posterior cervical foraminotomy (FEPCF) for adjacent two-level cervical radiculopathy.
Subjects and Methods: We conducted a retrospective case series of 43 patients with cervical radiculopathy involving two adjacent levels who underwent single-incision full-endoscopic posterior cervical foraminotomy (FEPCF) at Saint Paul General Hospital between July 2024 and July 2025.
Results: Mean age was 58.4 ± 12.0 years. All 43 procedures were completed through a single skin incision. Mean operative time was 56.9 ± 18.1 minutes and postoperative hospital stay was 3.8 ± 1.8 days. VAS decreased from 6.67 ± 1.04 preoperatively to 0.37 ± 0.79 at 6 months (mean decrease 6.30 points; 95% CI 5.89–6.72), and NDI decreased from 14.53 ± 4.38 to 4.12 ± 2.57 (mean decrease 10.42 points; 95% CI 9.51–11.33). Greenhouse–Geisser-corrected repeated-measures ANOVA showed significant changes over time for VAS (F[2.19, 92.03]=478.32; p<0.001) and NDI (F[1.94, 81.44]=383.22; p<0.001). At 6 months, 43/43 patients had Good or Excellent Modified MacNab outcomes. No postoperative complication was recorded in the retrospective dataset (0/43; exact 95% CI 0–8.2%).
Conclusion: In this retrospective case series, single-incision FEPCF for adjacent two-level cervical radiculopathy was technically feasible and was associated with substantial short-term improvement in the recorded VAS and NDI. No complication was recorded through 6 months, but the uncontrolled design, small sample, aggregate complication variable, and short follow-up do not permit conclusions about comparative effectiveness or long-term safety.