Articles Tập 67 Số CĐ15 25/09/2026

STUDY ON CERTAIN RELATIONSHIPS BETWEEN CLINICAL FEATURES, ENDOSCOPIC IMAGING, AND ANEMIA SEVERITY IN CHILDREN WITH PEPTIC ULCER DISEASE AT HUE UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL

Phan Hung Viet, Le Binh Phuong Nguyen, Nguyen Linh Giang, Tran Vinh Phu
DOI: 10.52163/yhc.v67iCD15.6704
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Abstract

Background: Anemia is the most common hematological disorder in children; however, anemia secondary to peptic ulcer disease has rarely been evaluated as an independent entity.

Objectives: To describe the clinical and endoscopic characteristics of children with peptic ulcer disease and to identify several factors associated with the severity of anemia in these patients. Methods: A cross-sectional study was conducted on 36 children diagnosed with peptic ulcer disease at Hue University of Medicine and Pharmacy Hospital.

Results: Peptic ulcer disease was predominantly observed in the 11-15 age group (86.1%) and in males (80.6%). The prevalence of anemia was 88.9%, with severe anemia accounting for 65.6% and iron deficiency anemia comprising 75.0%. The most common endoscopic lesion site was the duodenum (52.8%), ulcer size >10mm accounted for 83.3%, and the Helicobacter pylori infection rate was 63.9%. An iron-deficient diet and Helicobacter pylori (HP) infection were significantly associated with anemia severity (p < 0.001 and p = 0.03, respectively). In addition, HP infection was significantly associated with iron deficiency anemia (p = 0.046).

Conclusions: Severe anemia was highly prevalent among children with peptic ulcer disease in this study. HP infection and an iron-deficient diet were identified as factors associated with both the severity and subtype of anemia. Therefore, routine screening for anemia and its concurrent management should be considered in pediatric patients with peptic ulcer disease.

Keywords
Peptic ulcer disease, anemia, iron deficiency anemia, HP infection, children.
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