Articles Vol. 67 No. 9 30/09/2026

A SCOPING REVIEW OF THE TREATMENT FOR ALLERGIC RHINITIS USING ANTIHISTAMINE NASAL SPRAY

Nguyen Thi Hong Nhung, Do Ba Hung, Dao Trung Dũng, Tran Thi Thu Hang
DOI: 10.52163/yhc.v67i9.6686
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Abstract

Objective: To synthesize the results of studies on nasal antihistamine sprays for the treatment of allergic rhinitis. Methods: A scoping review. Results: Of the total number of studies searched in the Pubmed database, 12 met the inclusion criteria. All were intervention studies. To evaluate the effectiveness of nasal antihistamine sprays for allergic rhinitis, several methods are used, such as the Total Nasal Symptom Score (TNSS). Seven out of twelve studies applied the TNSS score, showing that after two weeks of treatment, the average TNSS score improved by 14.1% to 39.2% in the nasal antihistamine spray group compared to a 4.5% to 27% improvement in the placebo group. Assessment of four individual functional symptoms in the nose and eye symptoms were evaluated. The Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ) was used in 5 out of 12 studies, showing significant changes in the nasal antihistamine group compared to the control group. Conclusion: Nasal antihistamine spray is a good method to improve the symptoms of allergic rhinitis and significantly improving the quality of life for patients.

Keywords
Antihistamine nasal spray. 1.ĐẶT VẤN ĐỀ
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