Objective: To identify clinical, paraclinical, and treatment factors associated with early mortality in patients with cardiogenic shock. Subjects and Methods: A longitudinal descriptive study combining prospective and retrospective data was conducted on 70 patients with cardiogenic shock treated at the Institute of Cardiology, 108 Military Central Hospital from January 2024 to February 2026. Clinical characteristics, laboratory findings, treatment modalities, and prognostic scoring systems were collected and analyzed. Comparisons were made between survivors and non-survivors. Multivariable logistic regression analysis was performed to identify independent risk factors associated with early mortality. Results: The mean age was 69.3 ± 17 years, with a male-to-female ratio of approximately 1.8:1. The 30-day mortality rate was 47.1%. Factors associated with higher mortality included age ≥60 years (p=0.045), female sex (p=0.036), out-of-hospital cardiac arrest (p=0.005), SCAI stage E (p=0.019), use of ≥2 vasopressors (p=0.002), invasive mechanical ventilation (p=0.013), and intra-aortic balloon pump (IABP) support (p=0.049).
Regarding laboratory findings, the mortality group had lower arterial pH (7.22 ± 0.13 vs. 7.31 ± 0.12, p=0.003), higher anion gap (median 23.0 vs. 18.1, p=0.001), and lower SaO₂ (93.44 ± 7.25% vs. 96.58 ± 4.96%, p=0.041). Multivariable logistic regression analysis showed that the BOS.MA2 score was independently associated with early mortality (OR = 3.11; 95%CI: 1.22–7.97; p=0.018). Conclusion: Early mortality in patients with cardiogenic shock remains high. Older age, female sex, cardiac arrest, severe shock according to SCAI stage E, severe metabolic acidosis, and the need for intensive circulatory and respiratory support were associated with poor prognosis. The BOS.MA2 score demonstrated value in early mortality risk stratification.