Articles Vol. 67 No. 9 25/09/2026

A STUDY ON THE STATUS OF ANTIBIOTIC UTILIZATION IN THE SURGICAL DEPARTMENT OF MY PHUOC GENERAL HOSPITAL

Tran Quoc Tuan, Duong Thi Quynh, Le Ngoc Vu, Nguyen Thu Huong
DOI: 10.52163/yhc.v67i9.6640
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Abstract

Objectives: To evaluate antibiotic utilization among patients undergoing laparoscopic surgery at the Department of Surgery at My Phuoc General Hospital. Subjects and methods: A cross-sectional descriptive study was conducted on 194 patients undergoing laparoscopic surgery in the Department of Surgery at My Phuoc General Hospital from January 1, 2025 to June 30, 2025. Results: Among the 194 patients included in the study, females predominated over males (53.6% vs. 46.4%). The mean age of the participants was 39.29 ± 16.29 years, with the 18 – 64 age group being the most prevalent (81.4%). The majority of patients had no comorbidities (83.5%) and the average length of the hospital stay was 4.6 ± 1.71 days. Regarding clinical characteristics, appendicitis accounted for the highest proportion (71.6%), while other conditions such as inguinal hernia, ventral hernia and gallstones represented lower rates of 1.5%, 1% and 2.6% respectively. Regarding antibiotic use, Ceftazidime (a third-generation cephalosporin) was the most commonly utilized antibiotic, appearing in 131 medical records (48.52%), followed by Metronidazole in 54 records (20%). The β-lactam group was the predominant antibiotic class used (74.82%), whereas Aminoglycoside antibiotics and Fluoroquinolone antibiotics showed the lowest utilization rates at 3.7% and 1.48% respectively. The intravenous route was predominantly used (99.48%, n = 193). Most patients received antibiotic monotherapy (67%, n = 130), while the rate of triple antibiotic therapy was low (4.6%, n = 9). Short-term antibiotic use (≤ 5 days) constituted the majority of cases (76.3%). However, the implementation rate of antibiotic de-escalation strategies remained low at 18%.  Conclusion: Antibiotic therapy in the surgical department primarily utilized broad-spectrum agents, specifically the combination of Ceftazidime and Metronidazole, to ensure coverage against anaerobic pathogens in intra-abdominal infections. The intravenous route was used in the vast majority of cases (99.48%). While most patients received antibiotic monotherapy and short-course therapy (≤ 5 days), the rate of antibiotic de-escalation was low (18%). These findings highlight the necessity of enhanced adherence to antimicrobial stewardship principles to optimize therapeutic efficacy and mitigate the risk of antimicrobial resistance.

Keywords
Surgery, Anti-Bacterial Agents, Rational Antibiotic Use
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