Objective: To evaluate the effectiveness of pressure ulcer prevention using a spray containing highly oxidized Glyceride (Sanyrene) combined with routine care, and to identify some risk factors associated with pressure ulcers.
Subjects and methods: A prospective, descriptive, combined clinical intervention study was conducted on 72 patients at high or very high risk of pressure ulcers according to the Braden score (≤ 15 points), treated at the Intensive Care and Poison Center, Military Hospital 103 from January to August 2025.
Results: The average age of the study subjects was 73.19 ± 13.56 years; males accounted for 62.5%. The prevalence of pressure ulcers was 15.3%. Among the ulcer cases, grade I ulcers accounted for 54.5%, grade II ulcers for 36.4%, grade III ulcers for 9.1%, and no grade IV ulcers were recorded. The average time to ulcer onset was 4.6 ± 2.5 days. The most common ulcer locations were the sacrum and coccyx region (9.9%) and the heel (7.0%). Statistically significant factors associated with the risk of pressure ulcers included: higher SOFA score (p = 0.01), lower albumin (p = 0.02), higher blood lactate (p = 0.03), lower Braden score (p < 0.01), and lower frequency of turning (p = 0.04).
Conclusion: The use of high-oxidation Glyceride sprays combined with standard care measures helps maintain a low rate of pressure ulcers and limit the occurrence of severe ulcers in ICU patients. Factors such as disease severity, hypoalbuminemia, hyperlactateemia, and a low Braden score are associated with an increased risk of pressure ulcers.