Articles Vol. 67 No. 9 25/09/2026

SCREENING FOR SARCOPENIA IN OUTPATIENTS WITH TYPE 2 DIABETES MELLITUS IN HUNG YEN PROVINCE

Vu The Loc, Le Hoang Duy Nam
DOI: 10.52163/yhc.v67i9.6613
7 Views
0 Downloads
Abstract

Objective: To determine the prevalence of sarcopenia using the SARC-F, SARC-CalF, Ishii equation; and to evaluate the level of agreement among these tools in outpatients with type 2 diabetes mellitus.

Methods: A descriptive cross-sectional study was conducted on 240 outpatients with type 2 diabetes mellitus from December 2024 to February 2025 at two hospitals in Hung Yen province. Sarcopenia screening was performed using SARC-F, SARC-CalF, and the Ishii equation, and the level of agreement was assessed using the Kappa coefficient.

Results: The detection rates of sarcopenia were 25.8% by SARC-F, 38.7% by SARC-CalF, and 72.9% by the Ishii equation (in the subgroup aged ≥ 65 years). A significantly higher risk was observed in patients aged ≥ 65 years and those on insulin therapy for ≥ 5 years (p < 0.05). The Kappa coefficient between SARC-F and SARC-CalF was 0.448; within the ≥ 65 age group, the Kappa coefficients ranged from 0.206 to 0.377.

Conclusions: The detection rate of sarcopenia in type 2 diabetes patients differs significantly across the SARC-F, SARC-CalF, and Ishii formula. Sarcopenia risk is elevated in older age groups and with prolonged disease duration. Given the low-to-moderate agreement among these tools, implementing routine screening and combining multiple assessment methods are crucial for early diagnosis and prompt intervention.

References
[1]
[1] Ogurtsova K et al. IDF Diabetes Atlas: Global estimates for the prevalence of diabetes for 2015 and 2040. Diabetes Research and Clinical Practice, 2017, 128: 40-50. doi: 10.1016/j.diabres.2017.03.024. Google Scholar
[2]
[2] Wang T et al. Type 2 diabetes mellitus is associated with increased risks of sarcopenia and pre-sarcopenia in Chinese elderly. Scientific Reports, 2016, 6: 38937. doi: 10.1038/srep38937. Google Scholar
[3]
[3] Châu Thị Diễm Thanh, Nguyễn Văn Tân. Đánh giá tình trạng thiếu cơ và các yếu tố liên quan ở bệnh nhân cao tuổi đái tháo đường type 2 điều trị ngoại trú tại Bệnh viện Thống Nhất. Tạp chí Y học lâm sàng Bệnh viện Trung ương Huế, 2025, 17 (7): 110-119. doi: 10.38103/jcmhch.17.7.16 Google Scholar
[4]
[4] Cruz-Jentoft A.J, Bahat G et al. Sarcopenia: revised European consensus on definition and diagnosis. Age and Ageing, 2019, 48 (1): 16-31. doi: 10.1093/ageing/afy169. Google Scholar
[5]
[5] Barbosa-Silva T.G et al. Enhancing SARC-F: Improving sarcopenia screening in the clinical practice. Journal of the American Medical Directors Association, 2016, 17 (12): 1136-1141. doi: 10.1016/j.jamda.2016.08.004. Google Scholar
[6]
[6] Ishii S, Tanaka T et al. Development of a simple screening test for sarcopenia in older adults. Geriatrics & Gerontology International, 2014, 14 (Suppl): 93-101. doi: 10.1111/ggi.12197. Google Scholar
[7]
[7] Malmstrom T.K, Morley J.E. SARC-F: a simple questionnaire to rapidly diagnose sarcopenia. Journal of the American Medical Directors Association, 2013, 14 (8): 531-2. doi: 10.1016/j.jamda.2013.05.018. Google Scholar
[8]
[8] Feng L, Gao Q et al. Prevalence and risk factors of sarcopenia in patients with diabetes: a meta-analysis. J Clin Endocrinol Metab, 2022, 107 (5): 1470-1483. doi: 10.1210/clinem/dgab884. Google Scholar
[9]
[9] Guo J.Y, Yu K et al. Validity of the modified versions of SARC-F+EBM for sarcopenia screening and diagnosis in China: the PPLSS study. Asia Pacific Journal of Clinical Nutrition, 2024, 33 (1): 94-1013. doi: 10.6133/apjcn.202403_33(1).0010. Google Scholar
[10]
[10] Xu Z, Zhang P ET AL. Comparing SARC-CalF with SARC-F for screening sarcopenia in adults with type 2 diabetes mellitus. Frontiers in Nutrition, 2022, 9: 803924. doi: 10.3389/fnut.2022.803924. Google Scholar
[11]
[11] Chen X, Hou L ET AL. The accuracy of the Ishii score chart in predicting sarcopenia in the elderly community in Chengdu. BMC Geriatrics, 2021, 21 (1): 296. doi: 10.1186/s12877-021-02244-4. Google Scholar
[12]
[12] Luo S, Chen X et al. Cut-off points of the Ishii test to diagnosing severe sarcopenia among multi-ethnic middle-aged to older adults: results from the West China health and aging trend study. Frontiers in Medicine, 2023, 10: 1176128. doi: 10.3389/fmed.2023.1176128. Google Scholar
[13]
[13] Landis J.R, Koch G.G. The measurement of observer agreement for categorical data. Biometrics, 1977, 33 (1): 159-74. Google Scholar
[14]
[14] Ida S, Kaneko R, Murata K. SARC-F for screening of sarcopenia among older adults: a meta-analysis of screening test accuracy. Journal of the American Medical Directors Association, 2018, 19 (8): 685-689. doi: 10.1016/j.jamda.2018.04.001. Google Scholar