Objective: To describe the clinical, paraclinical, and microbiological characteristics of kidney stone patients with urinary tract infection who were treated before mini-percutaneous nephrolithotomy.
Methods: A retrospective descriptive study was conducted on 132 patients with kidney stones and urinary tract infection who achieved infection control before surgery at 108 Military Central Hospital between January 2025 and April 2026.
Results: The patients had a mean age of 62.29 ± 12.51, and females accounted for 55.3% of the study population. Flank pain was the most common symptom (97.7%), followed by dysuria (63.6%) and fever (46.2%). Leukocytosis was observed in 69.7% of patients, while pyuria was present in all cases. Renal pelvic stones associated with calyceal stones were the most common stone type (47.7%). Escherichia coli was the most frequently isolated pathogen (27.3%), followed by Pseudomonas aeruginosa (16.7%) and Klebsiella pneumoniae (14.4%). Gram-negative bacteria predominated (68.9%). Gram-negative isolates remained highly susceptible to Carbapenems and Aminoglycosides. Patients who received empirical antibiotic therapy consistent with antimicrobial susceptibility testing achieved negative urine cultures significantly faster than those receiving inappropriate empirical therapy (8.8 ± 2.7 vs. 12.4 ± 4.1 days, p < 0.001).
Conclusions: Gram-negative bacteria were the predominant pathogens in kidney stone patients with urinary tract infection. Appropriate empirical antibiotic selection was associated with a shorter duration of infection control before surgery.