Objective: To describe the clinical and paraclinical characteristics of halo nevi at the National Hospital of Dermatology and Venereology. Subjects and Methods: A descriptive case series study using convenience sampling was conducted on 51 patients diagnosed with halo nevi at the National Hospital of Dermatology and Venereology between August 2025 and June 2026. Results: The mean age was 17.78 ± 9.29 years, and the mean age of onset was 14.94 ± 9.24 years; the under-30 age group accounted for the highest proportion (90.2%). The gender distribution was 64.71% male and 35.29% female. Lesions were distributed on the trunk (45.10%) and the face (33.33%). The rate of comorbid vitiligo was 76.47%. Under Wood's lamp examination, 96.08% of halo nevus lesions showed a clearly defined white halo boundary against the surrounding healthy skin. Dermoscopy revealed a typical pattern in 90.2% of cases, characterized by a symmetrical, structureless white halo surrounding a central nevus. Histopathological examination in all 15 tested cases showed the presence of pigment-laden macrophages. Among 46 cases undergoing immunological testing, elevated FT3 was found in 32.61%, elevated FT4 in 4.35%, and elevated TSH in 78.26%; elevated TRAb levels were observed in 24 out of 42 cases (57.15%). Conclusion: Halo nevi primarily affect young people and mainly impact the patient's aesthetic appearance. Therefore, appropriate examination, monitoring, and intervention measures are necessary to improve the patient's quality of life and ensure close management.
CLINICAL AND PARACLINICAL CHARACTERISTICS OF HALO NEVUS AT THE NATIONAL HOSPITAL DERMATOLOGY AND VENEREOLOGY
0
Views
0
Downloads
Abstract
Keywords
halo nevus, depigmented halo, clinical & paraclinical characteristics
References
[1]
1. Weyant GW, Chung CG, Helm KF. Halo nevus: review of the literature and clinicopathologic findings. International journal of dermatology. Oct 2015;54(10):e433-5. doi:10.1111/ijd.12843
Google Scholar
[2]
2. Zhou H, Wu LC, Chen MK, Liao QM, Mao RX, Han JD. Factors Associated with Development of Vitiligo in Patients with Halo Nevus. Chinese medical journal. Nov 20 2017;130(22):2703-2708. doi:10.4103/0366-6999.218011
Google Scholar
[3]
3. Nguyễn Văn Thường. Hình ảnh lâm sàng, chẩn đoán và điều trị trong chuyên ngành Da liễu. vol 2. Nhà xuất bản Y hoc; 2019.
Google Scholar
[4]
4. Zeff RA, Freitag A, Grin CM, Grant-Kels JM. The immune response in halo nevi. Journal of the American Academy of Dermatology. Oct 1997;37(4):620-4. doi:10.1016/s0190-9622(97)70181-6
Google Scholar
[5]
5. DermNet New Zealand. Halo naevus (Sutton naevus). https://dermnetnz.org/topics/halo-naevus
Google Scholar
[6]
6. Picardo M, Dell'Anna ML, Ezzedine K, et al. Vitiligo. Nature reviews Disease primers. Jun 4 2015;1:15011. doi:10.1038/nrdp.2015.11
Google Scholar
[7]
7. Kolm I, Di Stefani A, Hofmann-Wellenhof R, et al. Dermoscopy patterns of halo nevi. Archives of dermatology. Dec 2006;142(12):1627-32. doi:10.1001/archderm.142.12.1627
Google Scholar
[8]
8. Ezzedine K, Eleftheriadou V, Whitton M, van Geel N. Vitiligo. Lancet (London, England). Jul 4 2015;386(9988):74-84. doi:10.1016/s0140-6736(14)60763-7
Google Scholar
[9]
9. Van Geel N, Speeckaert R, Taieb A, et al. Koebner's phenomenon in vitiligo: European position paper. Pigment cell & melanoma research. Jun 2011;24(3):564-73. doi:10.1111/j.1755-148X.2011.00838.x
Google Scholar
[10]
10. Porto AC, Blumetti TP, de Paula Ramos Castro R, et al. Recurrent halo nevus: Dermoscopy and confocal microscopy features. JAAD case reports. May 2017;3(3):256-258. doi:10.1016/j.jdcr.2017.02.020
Google Scholar