Articles Tập 67 Số CĐ13-HNKH Bệnh viện 19-8 10/09/2026

SURGICAL OUTCOMES OF ENDOSCOPIC REPAIR FOR SPONTANEOUS CEREBROSPINAL FLUID LEAKS

Nguyen Quang Trung, Ngo Van Hien
DOI: 10.52163/yhc.v67iCD13.6546
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Abstract

Objective: To evaluate the outcomes of endoscopic endonasal surgery for spontaneous cerebrospinal fluid leaks.

Methods: A scoping review. A literature search was conducted using the PubMed, Google Scholar, and ScienceDirect databases to search, screen relevant articles, and perform a descriptive synthesis of the outcomes of endoscopic endonasal repair for spontaneous CSF leaks.

Results: Twelve scientific articles were included in the study. A total of 330 surgical cases were analyzed. The typical patient demographic was middle-aged females presenting with overweight or obesity. This epidemiological characteristic is closely related to the pathogenesis of idiopathic intracranial hypertension. The most common skull base defect locations were concentrated at the cribriform plate and ethmoid roof. The multi-layer closure technique utilizing autologous grafts was the most prevalent reconstructive strategy. This method yielded a very high primary closure success rate, ranging from 79.2% to 100%, with the majority of centers achieving over 90%. The rate of severe complications was low; postoperative issues primarily consisted of olfactory dysfunction or local symptoms.

 

Conclusion: Endoscopic endonasal surgery demonstrates promising initial success rates in most centers. It is also a safe intervention, with a low incidence of serious complications such as meningitis or neurological injury.

Keywords
Spontaneous cerebrospinal fluid, endoscopic repair, surgical outcomes.
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