Articles Tập 67 Số CĐ14-HNKH Hội Hóa sinh Y học Việt Nam 17/09/2026

MEDICATION ADHERENCE AND ASSOCIATED FACTORS AMONG OUTPATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE AT HAI PHONG LUNG HOSPITAL IN 2025

Vu Thi Hoa, Trinh Thi Hien, Ngo Thu Hà, Luong Thi Thu Giang, Nguyen Thi Anh Thu, Nguyen Hai Ninh, Do Thi Ninh
DOI: 10.52163/yhc.v67iCD14.6542
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Abstract

Objective: To assess medication adherence and its associated factors among outpatients with chronic obstructive pulmonary disease (COPD) at Hai Phong Lung Hospital in 2025.

Methods: A cross-sectional study was conducted on 172 outpatients with chronic obstructive pulmonary disease (COPD). The Morisky Medication Adherence Scale (MMAS-8) was used to assess medication adherence. Data were analyzed using SPSS version 25.0, and multivariate logistic regression was performed to identify associated factors. 

Results: The proportion of patients with good medication adherence was 58.1%, while 41.9% demonstrated poor adherence. Independent factors associated with good medication adherence included age <65 years (OR = 3.52, 95% CI: 1.62–7.65), fewer COPD exacerbations during the previous 12 months (OR = 2.86–5.21), and the absence of comorbidities (OR = 2.15, 95% CI: 1.16–3.99), with p < 0.05 for all of these factors. 

Conclusion: Medication adherence in outpatient COPD patients is still suboptimal and affected by many factors; educational and supportive measures to ensure treatment adherence are needed, especially for elderly patients, those with frequent exacerbations, and those with comorbidities. Simultaneously, multicenter studies with larger sample sizes are needed to further confirm these findings.

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