Articles Tập 67 Số CĐ9-Hội Y học Giới tính 25/08/2026

IMPACT OF SHELL GINGER LEAF CAPSULE SUPPLEMENTATION FOR 8 WEEKS ON PLASMA MALONDIALDEHYDE AND SELECTED BLOOD BIOCHEMICAL PARAMETERS IN HEALTHY YOUNG MEN IN QUANG NINH

Hoang Thi Minh Phuong1,2, Vu Thi Thu Hien3,4, Le Danh Tuyen3,4, Tran Hoang Lan3,4, Vuong Thi Ho Ngoc3,4, Nguyen Thi Anh Nguyet3,4
1 Hanoi Medical College
2 Trường Cao đẳng Y tế Hà Nội
3 National Institute of Nutrition
4 Viện Dinh dưỡng Quốc gia
DOI: 10.52163/yhc.v67iCD9.6388
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Keywords
Shell Ginger, Alpinia zerumbet, malondialdehyde, MDA, glucose, LDL-C, oxidative stress.
Abstract

Objective: To evaluate the impact of Shell Ginger (Alpinia zerumbet) leaf capsules on plasma MDA levels and selected blood biochemical parameters in healthy young men after 8 weeks of supplementation.

Methods: A randomized controlled intervention study with a pre-post design was conducted in Quang Ninh province, Vietnam. A total of 55 participants completed the study, including 28 participants in the intervention group and 27 participants in the control group. The intervention group received Shell Ginger capsules (500 mg/capsule) at a dose of 9 capsules per day for 8 weeks, while the control group received no supplementation. Anthropometric parameters, plasma MDA levels, glucose, lipid profiles, and liver and kidney function indicators were assessed before and after the intervention.

Results: After 8 weeks, plasma MDA levels decreased significantly in the intervention group, from 2.1 nmol/mL to 1.8 nmol/mL. Post-intervention MDA levels were also significantly lower in the intervention group compared with the control group. Plasma glucose decreased from 5.1 mmol/L to 4.8 mmol/L, and LDL-C decreased from 2.7 mmol/L to 2.2 mmol/L in the intervention group. However, the post-intervention differences in glucose and LDL-C between the two groups were not statistically significant. No significant changes were observed in creatinine, AST, or ALT levels.

Conclusions: Shell Ginger capsules may contribute to improving oxidative status through reducing plasma MDA levels after 8 weeks of supplementation, with no evidence of adverse effects on liver or kidney function.

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