Articles Tập 67 Số CĐ9-Hội Y học Giới tính 25/08/2026

EPIDEMIOLOGICAL, CLINICAL AND LABORATORY CHARACTERISTICS OF PATIENTS WITH SYPHILIS AT THE SEXUALLY TRANSMITTED INFECTION CLINIC, NATIONAL HOSPITAL OF DERMATOLOGY AND VENEREOLOGY, 2025-2026

Tran Minh An1,2, Pham Thi Lan1,2,3,4
1 Department of Dermatology, Hanoi Medical University
2 Bộ môn Da liễu, Trường Đại học Y Hà Nội
3 National Hospital of Dermatology and Venereology
4 Bệnh viện Da Liễu Trung ương
DOI: 10.52163/yhc.v67iCD9.6377
0 Views
0 Downloads
Abstract

Objectives: To summarize epidemiological, clinical and risk-behavior features among first-visit patients with syphilis at the STI clinic, National Hospital of Dermatology and Venereology, 2025-2026.

Subjects and methods: A cross-sectional descriptive analysis was performed on 471 patients with confirmed syphilis and treatment indication. Demographic data, occupation, sexual behaviors, reasons for attendance, time from condomless sex to consultation, symptom duration, clinical signs and disease classification were extracted from the study records. Each variable was analyzed according to the number of valid observations.

Results: The mean age of the study subjects was 29.8 ± 11.0 years. The 25-34-year group accounted for 39.7%, followed by the 18-24-year group with 30.5%. Male patients accounted for 59.4%. The most frequent occupation was workers (26.1%), followed by non-disclosure of occupation (16.6%) and office employees (14.9%). Condomless sex was reported in 96.2%. The median interval from condomless sexual exposure to consultation was 30.0 (7.0-60.0) days; (66.7%) patients presented within 30 days after exposure. Among 149 patients with recorded symptom duration, the median duration before consultation was 17.5 (7.0-30.0) days. Early syphilis accounted for 34.7%, while cases with undetermined duration accounted for 62.8%. Mucocutaneous lesions and chancre were recorded in 21% and 11.7%, respectively.

Conclusions: Patients were mainly young adults, and condomless sex was highly frequent. The large proportion of cases with undetermined duration underlines the need for systematic recording of exposure history, symptom onset and previous treatment. Syphilis screening should be integrated with risk-behavior counseling, partner notification and testing for other sexually transmitted infections.

References
[1]
Rosset F, Celoria V, Delmonte S et al. The epidemiology of syphilis worldwide in the last decade. J Clin Med, 2025, 14 (15): 5308. doi: 10.3390/jcm14155308 Google Scholar
[2]
Trần Cẩm Vân, Hoàng Thị Ái Liên, Phạm Thị Minh Phương. Đặc điểm lâm sàng và một số yếu tố liên quan của bệnh giang mai tại Bệnh viện Da Liễu Trung ương. Tạp chí Y học Việt Nam, 2021, 503 (1): 114-117. doi: 10.51298/vmj.v503i1.707 Google Scholar
[3]
Nguyen H.T.T, Nguyen L.T, Hoang H.T.T et al. Increase in human immunodeficiency virus and syphilis prevalence and incidence among men who have sex with men, Vietnam 2015-2020. Int J STD AIDS, 2024, 35 (3): 197-205. doi: 10.1177/09564624231214583 Google Scholar
[4]
Zheng Y, Ye K, Ying M et al. Syphilis epidemic among men who have sex with men: a global systematic review and meta-analysis of prevalence, incidence, and associated factors. J Glob Health, 2024, 14: 04004. doi: 10.7189/jogh.14.04004 Google Scholar
[5]
Wang J, Zhu M, Smith R.D. Prevalence, incidence and risk factors of syphilis among men who have sex with men in China from 2013 to 2025: a systematic review and meta-analysis. BMC Infectious Diseases, 2025, 25 (1): 1821. doi: 10.1186/s12879-025-12176-8. Google Scholar
[6]
Nguyễn Duy Phúc và cộng sự. Tỷ lệ đồng nhiễm HIV - giang mai và một số yếu tố liên quan ở nam quan hệ tình dục đồng giới tại đồng bằng sông Cửu Long giai đoạn 2015-2022. Tạp chí Y học dự phòng, 2024, 34 (7): 107-116. doi: 10.51403/0868-2836/2024/2017 Google Scholar
[7]
Chen J.S, Levintow S.N, Tran H.V et al. HIV and STI prevalence and testing history among men who have sex with men in Hanoi, Vietnam. Int J STD AIDS, 2022, 33 (2): 193-201. doi: 10.1177/09564624211060185 Google Scholar
[8]
Cantisani C, Rega F, Ambrosio L et al. Syphilis, the great imitator - clinical and dermoscopic features of a rare presentation of secondary syphilis. Int J Environ Res Public Health, 2023, 20 (2): 1339. doi: 10.3390/ijerph20021339 Google Scholar