Articles Vol. 67 No. 8 28/08/2026

TREATMENT ADHERENCE AMONG HYPERTENSIVE OUTPATIENTS AT ME LINH GENERAL HOSPITAL AND SOME RELATED FACTORS IN 2025

Pham Xuan Thuy1,2, Nguyen Thu Uyen3,4
1 Transportation Department of Tuyen Quang Province
2 Sở Y tế tỉnh Tuyên Quang
3 Hoa Binh University
4 Trường Đại học Hòa Bình
DOI: 10.52163/yhc.v67i8.6323
16 Views
0 Downloads
Abstract

Objective: To describe treatment adherence among hypertensive outpatients at Me Linh General Hospital and analyze several related factors in 2025.

Subjects and Methods: A cross-sectional descriptive study was conducted on 361 hypertensive outpatients at Me Linh General Hospital in 2025. Data were collected using a structured questionnaire, including general characteristics, knowledge of hypertension and its treatment regimen, and the 8-item Morisky Medication Adherence Scale. Descriptive statistics and odds ratios with 95% confidence intervals were used to identify factors associated with non-adherence.

Results: The rate of adherence to antihypertensive medication was 83.9%, while 16.1% of patients were non-adherent. The proportion of patients with adequate knowledge of hypertension and its treatment regimen was 45.7%. Factors significantly associated with non-adherence included low educational level (OR=2.98; 95%CI: 1.62–5.48), absence of complications (OR=7.86; 95%CI: 3.63–17.02), inadequate knowledge (OR=2.54; 95%CI: 1.36–4.74), living alone (OR=6.00; 95%CI: 2.30–15.64), and lack of family reminders (OR=3.50; 95%CI: 1.57–7.79). Age group was not significantly associated with adherence (p>0.05).

Conclusion: Treatment adherence among hypertensive outpatients was relatively high; however, patients’ knowledge of hypertension and its treatment remained limited. Health education and stronger family support should be enhanced to improve treatment adherence.

References
[1]
Leslie Montealegre, Eulalia Amador, T. Pulido và các cộng sự. (2022), "MAIN FACTORS THAT DETERMINE ADHERENCE TO PHARMACOLOGICAL TREATMENT IN HYPERTENSIVE PATIENTS. SYSTEMATIC REVIEW", Journal of Hypertension, 40. Google Scholar
[2]
G. Parati, S. Kjeldsen, A. Coca và các cộng sự. (2021), "Adherence to Single-Pill Versus Free-Equivalent Combination Therapy in Hypertension: A Systematic Review and Meta-Analysis", Hypertension. Google Scholar
[3]
Ahmed Hossain, G. Ahsan, Mohammad Zakir Hossain và các cộng sự. (2025), "Medication adherence and blood pressure control in treated hypertensive patients: first follow-up findings from the PREDIcT-HTN study in Northern Bangladesh", BMC Public Health, 25. Google Scholar
[4]
Thi-Phuong-Lan Nguyen, C. Schuiling-Veninga, Thi Bach và các cộng sự. (2017), "Adherence to hypertension medication: Quantitative and qualitative investigations in a rural Northern Vietnamese community", PLoS ONE, 12. Google Scholar
[5]
Muhammad Arshed, Mehwish Kiran, Muhammad Farooq Umer và các cộng sự. (2025), "Prevalence and associated factors of adherence to antihypertensive medication: a nationwide cross-sectional study", BMC Public Health, 25. Google Scholar
[6]
A. Sharif, Syed Sharaf Ahmed Chowdhury, Md Zakir Hossain và các cộng sự. (2025), "Prevalence and determinants of medication adherence among hypertensive patients: An institution-based cross-sectional study", PLOS One, 20. Google Scholar
[7]
A. Bhagavathula, S. Shah và E. Aburawi (2021), "Medication Adherence and Treatment-Resistant Hypertension in Newly Treated Hypertensive Patients in the United Arab Emirates", Journal of Clinical Medicine, 10. Google Scholar
[8]
I. Hamdidouche, V. Jullien, P. Boutouyrie và các cộng sự. (2017), "Routine urinary detection of antihypertensive drugs for systematic evaluation of adherence to treatment in hypertensive patients", Journal of Hypertension, 35, tr. 1891. Google Scholar
[9]
E. Berra, M. Azizi, A. Capron và các cộng sự. (2016), "Evaluation of Adherence Should Become an Integral Part of Assessment of Patients With Apparently Treatment-Resistant Hypertension", Hypertension, 68, tr. 297. Google Scholar
[10]
Zhenzhen Xie, Kaifeng Liu, C. Or và các cộng sự. (2020), "An examination of the socio-demographic correlates of patient adherence to self-management behaviors and the mediating roles of health attitudes and self-efficacy among patients with coexisting type 2 diabetes and hypertension", BMC Public Health, 20. Google Scholar
[11]
Kumi Sagara, Kenichi Goto, M. Maeda và các cộng sự. (2024), "Medication adherence and associated factors in newly diagnosed hypertensive patients in Japan: the LIFE study", Journal of Hypertension, 42, tr. 718-726. Google Scholar
[12]
Sunita Sharma, C. Sharma, Suraj Sharma và các cộng sự. (2024), "Adherence to antihypertensive medication and its associated factors among patients with hypertension attending a tertiary hospital in Kathmandu, Nepal", PLOS ONE, 19. Google Scholar
[13]
Macquart De Terline, A. Kane, K. Kramoh và các cộng sự. (2019), "Factors associated with poor adherence to medication among hypertensive patients in twelve low and middle income Sub-Saharan countries", PLoS ONE, 14. Google Scholar