Articles Vol. 67 No. 8 28/08/2026

EARLY MOBILITY AND ASSOCIATED FACTORS IN MECHANICALLY VENTILATED NEUROSURGICAL PATIENTS AT AT THE ANESTHESIOLOGY AND INTENSIVE CARE CENTER OF BACH MAI HOSPITAL

Nguyen Kim Hoan1,2, Vu Van Kham1,2, Pham Viet Ha3,4,5,6, Doan Thu Huyen1,2
1 Anesthesia and Resuscitation Center, Bach Mai Hospital
2 Trung tâm Gây mê Hồi sức, Bệnh viện Bạch Mai
3 Thang Long University
4 Hai Phong International General Hospital
5 Trường Đại học Thăng Long
6 Bệnh viện Đa khoa Quốc tế Hải Phòng
DOI: 10.52163/yhc.v67i8.6299
21 Views
0 Downloads
Abstract

Objectives: (1) To evaluate the current status and feasibility of early mobilization in mechanically ventilated patients following neurosurgery; (2) To identify factors associated with early mobilization in this patient population. 

Subjects and methods: A cross-sectional study was conducted on 254 mechanically ventilated post-neurosurgical patients at the Anesthesiology and Resuscitation Center, Bach Mai Hospital from February to June 2025. Data were collected using a questionnaire, the Perme Score, and the ICU Mobility Scale (IMS). 

Results: The mean Perme Score improved significantly from 11.69 ± 4.9 at ICU admission to 18.4 ± 6.4 at ICU discharge (p < 0.001). The rate of early mobilization was 98.8%, with breathing exercises achieving good level (70.1%), limb exercises (59.8%), and walking exercises (30.3%). Factors associated with a higher risk of no improvement in mobility included: age ≥ 60 (OR = 3.65; p = 0.002), RASS < -2 (OR = 2.84; p = 0.01), Glasgow score ≤ 8 (OR = 2.5; p = 0.03), unstable hemodynamics (OR = 3.2; p = 0.005), and presence of comorbidities (OR = 4.7; p = 0.02). 

Conclusion: Early mobilization in mechanically ventilated patients after neurosurgery is implemented at a high rate and yields significant improvement. Risk factors should be carefully managed to optimize recovery outcomes.

References
[1]
Bộ Y tế. Quy trình chuyên môn khám, chữa bệnh chấn thương sọ não (Ban hành kèm theo Quyết định số 4068/QĐ-BYT, ngày 29 tháng 7 năm 2016). Google Scholar
[2]
Fugate J.E. Complications of Neurosurgery. Continuum (Minneap Minn) , 2015, 21 (5 Neurocritical Care): 1425-44. doi: 10.1212/CON.0000000000000227 Google Scholar
[3]
Klem H.E, Tveiten T.S, Beitland S et al. Early activity in mechanically ventilated patients - a meta-analysis. Tidsskr Nor Laegeforen, 2021, 141 (8). doi: 10.4045/tidsskr.20.0351. Print 2021 May 25. Google Scholar
[4]
Bailey P, Thomsen G.E, Spuhler V.J et al. Early activity is feasible and safe in respiratory failure patients. Crit Care Med, 2007, 35 (1): 139-145. doi: 10.1097/01.ccm.0000251130.69568.87 Google Scholar
[5]
TEAM Study Investigators, Hodgson C.L, Bailey M et al. Early active mobilization during mechanical ventilation in the ICU. N Engl J Med, 2022, 387 (19): 1747-1758. doi: 10.1056/NEJMoa2209083. Google Scholar
[6]
Boissonneau S, Tsiaremby M, Peyriere H et al. Postoperative complications in cranial and spine neurosurgery: a prospective observational study. J Neurosurg Sci, 2023, 67 (2): 157-167. Google Scholar
[7]
Võ Nguyễn Hoàng Phúc. Kết quả tập vận động sớm cho người bệnh thở máy tại Khoa Hồi sức tích cực, Bệnh viện Đại học Y dược thành phố Hồ Chí Minh. Tạp chí Y học Việt Nam, 2022, 524 (3): 337-340. doi: 10.51298/vmj.v524i1B.4794 Google Scholar
[8]
Lê Thị Mỹ Tiên. Hồi phục chức năng vận động ở người bệnh chấn thương sọ não nặng sau phẫu thuật mở nắp sọ giảm áp. Tạp chí Nghiên cứu Y học, 2025, 192 (07): 374-384. doi: 10.52852/tcncyh.v192i7.3685 Google Scholar
[9]
Timenetsky K.T, Serpa Neto A, Lazarin A.C et al. The Perme mobility index: a new concept to assess mobility level in patients with coronavirus (COVID-19) infection. PLoS One, 2021, 16 (4): e0250180. doi: 10.1371/journal.pone.0250180. Google Scholar
[10]
Yen H.C, Chuang H.J, Hsiao W. L et al. Assessing the impact of early progressive mobilization on moderate-to-severe traumatic brain injury: a randomized controlled trial. Crit Care, 2024, 28 (1): 172. doi: 10.1186/s13054-024-04940-0. Google Scholar
[11]
Bùi Xuân Cương. Một số đặc điểm dịch tễ học người bệnh chấn thương sọ não tại Bệnh viện Việt Đức. Tạp chí Y học Việt Nam, 2021, 502 (1): 20-25. doi: 10.51298/vmj.v502i1.546 Google Scholar
[12]
Dres M, Dubé B.P, Mayaux J et al. Coexistence and Impact of limb muscle and diaphragm weakness at time of liberation from mechanical ventilation in medical intensive care unit patients. Am J Respir Crit Care Med, 2017, 195 (1): 57-66. doi: 10.1164/rccm.201602-0367OC. Google Scholar
[13]
Brock C, Marzano V, Green M et al. Defining new barriers to mobilisation in a highly active intensive care unit-have we found the ceiling? An observational study. Heart & Lung, 2018, 47 (4): 380-385. doi: 10.1016/j.hrtlng.2018.04.004. Google Scholar
[14]
Jolley S.E, Moss M, Needham D.M et al. Point prevalence study of mobilization practices for acute respiratory failure patients in the United States. Crit Care Med, 2017, 45 (2): 205-215. doi: 10.1097/CCM.0000000000002058. Google Scholar
[15]
Girard T.D, Alhazzani W, Kress J.P et al. An Official American Thoracic Society/American College of Chest Physicians Clinical Practice Guideline: Liberation from mechanical ventilation in critically ill adults. Am J Respir Crit Care Med, 2017, 195 (1): 120-133. doi: 10.1164/rccm.201610-2075ST. Google Scholar