Articles T67 Số CDD10 - HN Bệnh viện Nhi Đồng 2 - HN Trường Đại học Nguyễn Tất Thành

CLINICAL AND PARACLINICAL FINDINGS OF PEDIATRIC PATIENTS WITH SEPTIC SHOCK TREATED AT NGHE AN MATERNITY AND PEDIATRIC HOSPITAL

Nguyen Thi Trang1,2, Pham Thi Thu Hien3,4, Nguyen Anh Nham3,4, Ho To Nga3,4, Ngo Anh Vinh5,6, Nguyen Doan Phong7,8, Trieu Ngoc Thao7,8, Chu Thi Ha7,8, Dang Phuong Thuy5,6
1 Vinmec Hai Phong International General Hospital
2 Bệnh viện đa khoa quốc tế Vinmec Hải Phòng
3 Nghe An Obstetrics and Pediatrics Hospital
4 Bệnh viện Sản Nhi Nghệ An
5 Vietnam National Children's Hospital
6 Bệnh viện Nhi Trung ương
7 Department of Pediatrics - Hai Phong University of Medicine and Pharmacy
8 Bộ môn Nhi - Trường Đại học Y Dược Hải Phòng
DOI: 10.52163/yhc.v67icd10.6220
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Keywords
Septic shock; pediatrics; lactate; intensive care.
Abstract

Objective: To describe the clinical and paraclinical characteristics of pediatric patients with septic shock treated at Nghe An Obstetrics and Pediatrics Hospital.

Subjects and Methods: A cross-sectional descriptive study was conducted on 59 pediatric patients diagnosed with septic shock and treated in the Intensive Care Unit (ICU) of Nghe An Obstetrics and Pediatrics Hospital from September 2023 to August 2025. Collected variables included demographic characteristics, clinical manifestations, and paraclinical parameters (hematology, coagulation profile, biochemistry, and arterial blood gas) assessed at hospital admission.

Results: The median age was 16 months (IQR: 8–72), with the highest proportion in the group under 12 months (44.1%). Males predominated over females (64.4%). The primary source of infection was the respiratory tract (55.9%). Common clinical manifestations included fever (88.1%), dyspnea (61.0%), and altered mental status (45.8%). Signs of peripheral hypoperfusion were frequently observed, particularly prolonged capillary refill time (CRT >3 seconds) (69.5%). Laboratory findings showed leukocytosis, elevated C-reactive protein (CRP) and procalcitonin levels, along with coagulopathy and metabolic acidosis. Blood lactate levels were elevated, with a median of 3.8 mmol/L (IQR: 2.6–6.2).

Conclusion: Septic shock in children is characterized by peripheral hypoperfusion, systemic inflammatory response, and metabolic acidosis. Common laboratory abnormalities include leukocytosis, elevated CRP and procalcitonin, coagulation disorders, and increased blood lactate levels.

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