Articles T67 Số CDD10 - HN Bệnh viện Nhi Đồng 2 - HN Trường Đại học Nguyễn Tất Thành

MORTALITY PROGNOSTIC VALUE OF SIMPLIFIED CLINICAL FRAILTY SCALE (s-CFS) IN ELDERLY PATIENTS WITH COMMUNITY-ACQUIRED PNEUMONIA AT THONG NHAT HOSPITAL IN 2024-2025

Pham Thi Ngoc Anh1,2, Nguyen Van Tri3,4, Cao Thanh Ngoc1,2, Ngo The Hoang5,6, Nguyen Tran To Uyen2,7
1 University of Medicine and Pharmacy at Ho Chi Minh City -
2 Đại học Y dược Thành phố Hồ Chí Minh
3 Nguyen Tat Thanh University
4 Đại học Nguyễn Tất Thành
5 Department of Respiratory Medicine, Thong Nhat Hospital
6 Khoa Nội Hô hấp, Bệnh viện Thống Nhất
7 University of Medicine and Pharmacy at Ho Chi Minh City
DOI: 10.52163/yhc.v67icd10.6196
0 Views
0 Downloads
Abstract

Objective: Recent studies indicate that the use of frailty assessment methods is an important factor in improving in-hospital mortality prognosis in elderly patients, especially in cases of acute infections such as community-acquired pneumonia. Therefore, this study was conducted to evaluate the predictive value of the simplified clinical frailty scale (s-CFS) for in-hospital mortality among elderly patients with community-acquired pneumonia.

Materials and methods: A prospective observational study with in-hospital follow-up was conducted on 229 patients aged  ≥60 years who were diagnosed with community-acquired pneumonia and admitted to the Department of Respiratory Medicine at Thong Nhat Hospital. The prognostic performance of the s-CFS for predicting in-hospital mortality was evaluated using sensitivity, specificity, and the area under the ROC curve (AUC).

Results: From August 2024 to March 2025, one hundred sixty-nine patients (73,8%) were diagnosed with frailty. The in-hospital mortality rate was 6,1%. s-CFS has a predictive value for in-hospital mortality with AUC = 0,718 (p = 0,004).

Conclusion: The simplified clinical frailty scale is a simple and practical tool for predicting mortality and may be recommended for use in clinical practice.

References
[1]
Li S, Li L, Wang S, et al. Clinical characteristics and risk factors of hospital mortality in elderly patients with community-acquired pneumonia. Front Med. 2025;12. Google Scholar
[2]
Nguyen VT et al. Simplified clinical frailty scale design, validation, and adaptation in older patients. European Review For Medical and Pharmacological Sciences. 2024;28(5):1857–1863. Google Scholar
[3]
Mandell LA, Wunderink RG, Anzueto A, et al. Infectious Diseases Society of America/American Thoracic Society Consensus Guidelines on the Management of Community-Acquired Pneumonia in Adults. Clin Infect Dis. 2007;44(Supplement_2):S27–S72. Google Scholar
[4]
Nguyễn Quốc Việt. Khảo sát tỉ lệ suy yếu trên bệnh nhân cao tuổi mắc viêm phổi cộng đồng điều trị nội trú [Luận văn chuyên khoa 2]. Đại học Y dược Thành phố Hồ Chí Minh; 2023. Google Scholar
[5]
Rosario BH, Quah JL, Chang TY, et al. Validation of the Hospital Frailty Risk Score in older adults hospitalized with community‐acquired pneumonia. Geriatr Gerontol Int. 2024;24(Suppl 1):135–141. Google Scholar
[6]
Jabeen F, Mishra A, Mateen S, et al. Pneumonia in Geriatric Patients and Prediction of Mortality Based on the Pneumonia Severity Index (PSI), CURB-65, Frailty Index (FI), and FI-Lab21 Scores. Cureus. 2024;16(6):e61719. Google Scholar
[7]
Carter B, Keevil VL, Anand A, et al. The Prognostic and Discriminatory Utility of the Clinical Frailty Scale and Modified Frailty Index Compared to Age. Geriatrics. 2022;7(5):87. Google Scholar
[8]
Zan YM, Zheng TP, Wang Y, et al. Combining a Frailty Index Based on Laboratory Data and Pneumonia Severity Assessments to Predict In-Hospital Outcomes in Older Adults with Community-Acquired Pneumonia. The Journal of nutrition, health and aging. 2023;27(4):270–276. Google Scholar
[9]
Lee JH, Park YS, Kim MJ, et al. Clinical Frailty Scale as a predictor of short-term mortality: A systematic review and meta-analysis of studies on diagnostic test accuracy. Academic Emergency Medicine. 2022;29(11):1347–1356. Google Scholar