Articles Vol. 67 No. Số CĐ12- Bệnh viện Ung bướu Nghệ An (2026) 14/08/2026

FACTORS ASSOCIATED WITH QUALITY OF LIFE AMONG CANCER PATIENTS RECEIVING EXCLUSIVE PALLIATIVE CARE AT NGHE AN ONCOLOGY HOSPITAL

Nguyen Van Cong1,2, Nguyen Van Vinh1,2, Lo Thi Thanh Nhan1,2, Dinh Ngoc Lam1,2, Nguyen Thi Huong1,2
1 Department of Palliative Care, Nghe An Oncology Hospital
2 Khoa Điều trị giảm nhẹ, Bệnh viện Ung Bướu Nghệ An
DOI: 10.52163/yhc.v67iCD12.6165
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Abstract

Objective: To analyze factors associated with quality of life among cancer patients receiving exclusive palliative care at Nghe An Oncology Hospital.

Subjects and methods: A cross-sectional descriptive study was conducted among 130 cancer patients receiving exclusive palliative care at Nghe An Oncology Hospital from February to August 2025. Quality of life was assessed using the EORTC QLQ-C30 version 3.0. Anxiety and depression were evaluated using the HADS scale. Factors associated with quality of life were analyzed using appropriate statistical tests.

Results: The mean global health status score according to the EORTC QLQ-C30 was 39.61 ± 22.92. Among functional domains, cognitive functioning had the highest score (56.41 ± 27.94 points), while role functioning had the lowest score (39.10 ± 31.24 points). The symptoms with the greatest impact on quality of life were fatigue (62.30 ± 28.26 points), pain (58.20 ± 33.02 points), insomnia (57.43 ± 33.72 points), and financial difficulties (71.28 ± 30.43 points). Global health status differed significantly between age groups (p = 0.044). Fatigue and pain scores showed statistically significant differences according to disease stage (p = 0.031 and p = 0.013, respectively). Anxiety and depression were negatively correlated with functional domains and global health status, while positively correlated with symptom severity.

Conclusion: Cancer patients receiving exclusive palliative care had poor quality of life, which was substantially affected by physical symptoms, functional impairment, financial difficulties, and psychological problems.

References
[1]
Bray F et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer Journal for Clinicians, 2024, 74 (3): 229-263. doi: 10.3322/caac.21834. Google Scholar
[2]
Palliative care. https://www.who.int/westernpacific/health-topics/palliative-care. Google Scholar
[3]
Sanders J.J et al. Palliative care for patients with cancer: ASCO guideline update. Journal of Clinical Oncology, 2024, 42 (19): 2336-2357. doi: 10.1200/JCO.24.00542. Google Scholar
[4]
Aaronson N.K et al. The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst, 1993, 85 (5): 365-376. doi: 10.1093/jnci/85.5.365. Google Scholar
[5]
Bui Vinh Quang et al. Quality of life among newly admitted patients to cancer hospital in Vietnam and associated factors. Health Psychol Open, 2020, 7 (2): 2055102920953049. doi: 10.1177/2055102920953049. Google Scholar
[6]
Husson O et al. The relation between information provision and health-related quality of life, anxiety and depression among cancer survivors: a systematic review. Annals of Oncology, 2011, 22 (4): 761-772. doi: 10.1093/annonc/mdq413. Google Scholar
[7]
Quinten C et al. Baseline quality of life as a prognostic indicator of survival: a meta-analysis of individual patient data from EORTC clinical trials. Lancet Oncol, 2009, 10 (9): 865-71. doi: 10.1016/S1470-2045(09)70200-1. Google Scholar
[8]
Levy M.H et al. NCCN clinical practice guidelines in oncology: palliative care. J Natl Compr Canc Netw, 2009, 7 (4): 436-73. doi: 10.6004/jnccn.2009.0031. Google Scholar
[9]
Palliative care. https://www.who.int/en/news-room/fact-sheets/detail/palliative-care. Google Scholar
[10]
Marzorati C et al. Psychosocial factors associated with quality of life in cancer patients undergoing treatment: an umbrella review. Health Qual Life Outcomes, 2025, 23 (1): 31. doi: 10.1186/s12955-025-02357-z. Google Scholar
[11]
Mai ThuTrang và cộng sự. Đánh giá chất lượng cuộc sống cảu bệnh nhân ung thư giai đoạn III, IV theo bộ công cụ EORTC QLQ-C30 tại Bệnh viện Đa khoa tỉnh Thái Bình. Tạp chí Khoa học và Công nghệ Đại học Thái Nguyên, 2020, 225 (08): 388-394. Google Scholar
[12]
Mitchell A.J et al. Prevalence of depression, anxiety, and adjustment disorder in oncological, haematological, and palliative-care settings: a meta-analysis of 94 interview-based studies. Lancet Oncology, 2011, 12 (2): 160-74. doi: 10.1016/S1470-2045(11)70002-X. Google Scholar
[13]
Salvetti M.D.G et al. Prevalence of symptoms and quality of life of cancer patients. Rev Bras Enferm, 2020, 73 (2): e20180287. doi: 10.1590/0034-7167-2018-0287. Google Scholar