Articles Vol. 67 No. CĐ11-NCKH 31/07/2026

PERFORMANCE OF THE METS-IR INDEX IN IDENTIFYING POOR GLYCEMIC CONTROL IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

Bui Thi Minh Phuong1,2, Nguyen Thi Minh Thai1,2
1 Thai Binh University of Medicine and Pharmacy
2 Trường Đại học Y Dược Thái Bình
DOI: 10.52163/yhc.v67iCD11.6036
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Keywords
METS-IR, HbA1c, type 2 diabetes mellitus, poor glycemic control, insulin resistance.
Abstract

Objective: To evaluate the ability of the METS-IR index to identify HbA1c ≥ 7% in patients with type 2 diabetes mellitus.

Methods: A cross-sectional study was conducted among 189 patients with type 2 diabetes mellitus. Poor glycemic control was defined as HbA1c ≥ 7%. The discriminative ability of METS-IR was assessed using the receiver operating characteristic curve, a 2×2 contingency table, and logistic regression.

Results: The proportion of patients with HbA1c ≥ 7% was 36.5%. The optimal METS-IR cutoff in the study sample was 36.46, with an AUC of 0.669, sensitivity of 71.0%, specificity of 60.0%, positive predictive value of 50.5%, and negative predictive value of 78.3%. METS-IR ≥ 36.46 was significantly associated with HbA1c ≥ 7%, with an OR of 3.675 in the univariate model and an OR of 4.053 after multivariable adjustment. The observed AUC of METS-IR was higher than those of BMI, waist circumference, triglycerides, and triglyceride/HDL-C.

Conclusion: METS-IR showed moderate ability to identify HbA1c ≥ 7% in patients with type 2 diabetes mellitus.

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