Articles Vol. 67 No. 7 26/07/2026

GIANT SOLITARY FIBROUS TUMOR OF THE PLEURA TREATED AT HANOI ONCOLOGY HOSPITAL: A RARE CASE REPORT

Pham Dac Dong1,2, Pham Dac Dong1,2, Phan Le Thang1,2, Nguyen Van An1,2, Pham Van Hoan1,2
1 Department of Surgery, Hanoi Cancer Hospital
2 Khoa Ngoại yêu cầu, Bệnh viện Ung bướu Hà Nội
DOI: 10.52163/yhc.v67i7.5967
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Abstract

Solitary fibrous tumor of the pleura (SFTP) is a rare neoplasm, accounting for less than 5% of all primary pleural tumors. While typically benign and slow-growing, SFTP can reach a massive size, leading to severe compression of mediastinal structures and manifest respiratory symptoms. Giant SFTP (gSFTP) is defined as an SFTP measuring over 15 cm or occupying more than 40% of the affected hemithorax. We report a case of a giant benign SFTP in a 64-year-old female patient who presented with progressive dyspnea and right-sided chest pain. Chest computed tomography (CT) revealed a large, solid mass occupying almost the entire right pleural cavity, without invasion into the lung parenchyma or mediastinal structures.The pathology report from the preoperative needle biopsy revealed a solitary fibrous tumor of the pleura. The patient underwent complete tumor resection via a right thoracotomy. The excised mass measured 21x21 cm and weighed over 2 kg. Histopathological examination confirmed a solitary fibrous tumor of the pleura. Postoperatively, the patient recovered well with no signs of recurrence during a 12-month follow-up period. The patient was then instructed to continue with regular check-ups. This case highlights the clinical importance of early recognition and prompt surgical management of giant pleural tumors, despite their rarity.

References
[1]
Perrotta F, Cerqua FS, Cammarata A, et al. Integrated therapeutic approach to giant solitary fibrous tumor of the pleura: report of a case and review of the literature. Open Medicine. 2016;11(1):220-225. doi:10.1515/med-2016-0042 Google Scholar
[2]
Crnjac A, Veingerl B, Vidovic D, Kavalar R, Hojski A. Giant solitary fibrous tumour of the pleura. Case report and review of the literature. Radiology and Oncology. 2015;49(4):395-401. doi:10.2478/raon-2014-0036 Google Scholar
[3]
Abu Arab W. Solitary fibrous tumours of the pleura. European Journal of Cardio-Thoracic Surgery. 2012;41(3):587-597. doi:10.1093/ejcts/ezr009 Google Scholar
[4]
Wassim C, Imen B, Amina A, Mahdi A, Hazem Z, Adel M. Surgical management of giant solitary fibrous tumors of the pleura: Two case reports. International Journal of Surgery Case Reports. 2024;122:110109. doi:10.1016/j.ijscr.2024.110109 Google Scholar
[5]
Biçer M, Yaldız S, Gürsoy S, Ülğan M. A case of giant benign localized fibrous tumor of the pleura1. European Journal of Cardio-Thoracic Surgery. 1998;14(2):211-213. doi:10.1016/S1010-7940(98)00166-3 Google Scholar
[6]
Yao K, Zhu L, Wang L, et al. Resection of giant malignant solitary fibrous pleural tumor after interventional embolization: a case report and literature review. J Cardiothorac Surg. 2022;17(1):134. doi:10.1186/s13019-022-01881-z Google Scholar
[7]
Km HP, Fc N, Cd S, et al. Solitary fibrous tumors of the pleura: results of surgical treatment and long-term prognosis. The Journal of thoracic and cardiovascular surgery. 2009;138(1). doi:10.1016/j.jtcvs.2009.01.026 Google Scholar
[8]
T K, J W. Recurrence of a malignant solitary fibrous tumor of the pleura 17 years after primary tumor resection - A case report. Respiratory medicine case reports. 2019;28. doi:10.1016/j.rmcr.2019.100895 Google Scholar
[9]
Martin-Broto J, Stacchiotti S, Lopez-Pousa A, et al. Pazopanib for treatment of advanced malignant and dedifferentiated solitary fibrous tumour: a multicentre, single-arm, phase 2 trial. The Lancet Oncology. 2019;20(1):134-144. doi:10.1016/S1470-2045(18)30676-4 Google Scholar