Articles Vol. 67 No. 7 26/07/2026

INVESTIGATING DEPRESSIVE DISORDERS IN PEMPHIGUS PATIENTS UNDERGOING GLUCOCORTICOSTEROID TREATMENT AT HO CHI MINH CITY HOSPITAL OF DERMATO-VENEREOLOGY

Vo Thi Doan Phuong1,2, Nguyen Truc Quynh1,2, Nguyen Thi Khanh Hang1,2, Thai Van Thong1,2, Nguyen Thi Phan Thuy1,2
1 Ho Chi Minh city Hospital of Dermato-Venereology
2 Bệnh viện Da Liễu thành phố Hồ Chí Minh
DOI: 10.52163/yhc.v67i7.5932
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Keywords
Pemphigus vulgaris, Pemphigus foliaceus, depression.
Abstract

Objective: To investigate the prevalence of depression among Pemphigus patients undergoing Glucocorticosteroids treatment at the clinical departments of Ho Chi Minh city Hospital of Dermato-Venereology.

Methods: A cross-sectional study was conducted on 140 patients with clinically and histologically confirmed Pemphigus.

Results: Among the 140 patients, 109 were diagnosed with Pemphigus vulgaris and 31 with Pemphigus foliaceus. Female patients predominated (61.4%). Most patients had mild to moderate disease severity according to the PDAI score (65% and 33.6%, respectively). A relatively high prevalence of depression was observed (43.6%), with the majority classified as mild depression (38.6%). No patients were diagnosed with severe depression.

Conclusion: Comprehensive dermatological management may contribute to reducing the severity of depression in patients with Pemphigus.

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