Articles Tập 67 Số CĐ9-Hội Y học Giới tính 29/07/2026

TWO CASES OF LAPAROSCOPIC EXCISION OF A BLEEDING SEMINAL VESICLE CYST IN ZINNER SYNDROME AT 108 MILITARY CENTRAL HOSPITAL AND VIET DUC UNIVERSITY HOSPITAL

Trinh Hoang Giang1,2, Nguyen Tuan Dat3,4, Nguyen Van Phuc3,4, Bui Van Quang1,2, Phan Le Nhat Long3,4, Pham Duc Manh3,4, Nghiem Trung Dung3,4, Le Duc Phuc3,4, Pham Thi Thu Trang1,2, Nguyen Dang Kien1,2
1 Viet Duc University Hospital
2 Bệnh viện Hữu nghị Việt Đức
3 108 Military Central Hospital
4 Bệnh viện Trung ương Quân đội 108
DOI: 10.52163/yhc.v67iCD9.5801
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Keywords
Hematospermia, seminal vesicle cyst, laparoscopic seminal vesicle resection, Zinner syndrome.
Abstract

Objective: To evaluate the outcomes of laparoscopic seminal vesicle cyst excision in patients presenting with hematospermia and to review the literature on the rare Zinner syndrome.

Subjects and methods: A retrospective cross-sectional descriptive study was conducted on two male patients with hemorrhagic seminal vesicle cysts who underwent laparoscopic surgery at 108 Military Central Hospital and Viet Duc University Hospital. Clinical characteristics, imaging findings, operative details, perioperative outcomes, and postoperative follow-up data were analyzed.

Results: Patient 1 was a 16-year-old male diagnosed with a left seminal vesicle cyst measuring 60 × 40 mm associated with left renal agenesis and a solitary right kidney. Laparoscopic excision was performed using four trocars (three 10-mm and one 5-mm trocars). Operative time was 90 minutes with blood loss less than 50 ml. No intraoperative complications occurred. The patient was discharged after 5 days. Histopathology revealed a seminal vesicle cyst with chronic fibrotic stromal inflammation.

Patient 2 was a 24-year-old male diagnosed with a right seminal vesicle cyst measuring 70 × 35 mm associated with right renal agenesis and a solitary left kidney. Surgery was completed laparoscopically using four trocars (two 10-mm and two 5-mm trocars). Operative time was 95 minutes with negligible blood loss. No intraoperative complications were observed. Length of hospital stay was 5 days. Histopathological examination demonstrated a benign seminal vesicle cyst with fibrotic connective tissue.

At 6-month follow-up, hematospermia resolved completely in both patients; however, semen analysis showed decreased sperm quantity and quality.

Conclusion: Seminal vesicle cysts are rare lesions commonly associated with Zinner syndrome. Cysts larger than 5 cm are more likely to cause clinical symptoms. Laparoscopic excision is a safe and effective minimally invasive treatment for symptomatic seminal vesicle cysts. Zinner syndrome may adversely affect male fertility despite successful surgical management.

References
[1]
Trịnh Hoàng Giang, Bùi Văn Quang, Phạm Thị Thu Trang. Đánh giá kết quả phẫu thuật nội soi ổ bụng cắt túi tinh điều trị xuất tinh máu tại Trung tâm Nam học, Bệnh viện Hữu nghị Việt Đức từ 2021 đến 2024. Tạp chí Y học cộng đồng, 2024, 65 (CĐ 4): 244-251. doi: 10.52163/yhc.v65iCD4.1181 Google Scholar
[2]
Huang Y, Han B et al. Zinner’s syndrome in two young middle-aged men: a case report and review of the literature. BMC Urol, 2025, 25 (1): 129. doi: 10.1186/s12894-025-01806-7. Google Scholar
[3]
Sheih C.P et al. Cystic dilatations within the pelvis in patients with ipsilateral renal agenesis or dysplasia. The Journal of Urology, 1990, 144 (2, Pt 1): 324-327. doi: 10.1016/s0022-5347(17)39444-2. Google Scholar
[4]
Liu T, Li X et al. Zinner syndrome: an updated pooled analysis based on 214 cases from 1999 to 2020: systematic review. Ann Palliat Med, 2021, 10 (2): 2271-2282. doi: 10.21037/apm-20-1997. Google Scholar
[5]
Morante-Ruiz M, Tornero-Romero F et al. Zinner’s syndrome and retroperitoneal fibrosis: an unknown association. Eur J Case Rep Intern Med. 2024, 11 (2): 004246. doi: 10.12890/2024_004246. Google Scholar
[6]
Van den Ouden D et al. Diagnosis and management of seminal vesicle cysts associated with ipsilateral renal agenesis: a pooled analysis of 52 cases. European Urology, 1998, 33 (5): 433-440. doi: 10.1159/000019632. Google Scholar
[7]
Boui M, Edderai M et al. Zinner syndrome: a rare congenital cause of infertility. Radiol Case Rep, 2024, 19 (12): 5586-5588. doi: 10.1016/j.radcr.2024.08.029. Google Scholar
[8]
Talwar H.V et al. Robot-assisted laparoscopic approach in a patient of Zinner syndrome with hematuria: a rare presentation. J Midlife Health, 2021, 12 (1): 79-81. doi: 10.4103/jmh.JMH_49_20 Google Scholar