Articles Tập 67 Số CĐ9-Hội Y học Giới tính 29/07/2026

ERECTILE DYSFUNCTION AND ASSOCIATED FACTORS FOLLOWING RADICAL CYSTECTOMY

Pham Huu Doan1,2
1 Binh Dan Hospital
2 Bệnh viện Bình Dân
DOI: 10.52163/yhc.v67iCD9.5796
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Abstract

Objective: To determine the prevalence of erectile dysfunction and identify associated factors following radical cystectomy for bladder cancer.

Methods: A prospective longitudinal study was conducted on 117 male patients undergoing radical cystectomy at Binh Dan Hospital (from November 2020 to November 2024). Erectile function was assessed using the IIEF-5 score before surgery and at 3 months, 6 months, 12 months postoperatively.

Results: The patients had a mean age of 60.1 ± 9.6 years. The mean preoperative IIEF-5 score was 17.14, with 32.5% having normal erectile function. Postoperatively, mean IIEF-5 scores declined to 6.0, 6.5, and 11.35 points at 3 months, 6 months, and 12 months, respectively. At 3 months, all patients had severe erectile dysfunction; no patient recovered to normal function at 12 months. Preoperative IIEF-5 score was the only independent predictor (β = 0.32; 95% CI: 0.23-0.41; p < 0.001).

Conclusion: Erectile dysfunction is a common complication following radical cystectomy, with significant decline and limited recovery at 12 months. Preoperative sexual function assessment, nerve-sparing techniques when oncologically appropriate, and postoperative penile rehabilitation should be integrated into long-term patient care.

References
[1]
Pronk C.E, Veskimäe E, van de Putte E.E.F et al. Longitudinal sexual function and quality of life after radical cystectomy in men with bladder cancer. Front Urol, 2023, 3: 1100516. doi: 10.3389/fruro.2023.1100516. Google Scholar
[2]
Loh-Doyle J.C, Bhanvadia S.K, Han J et al. Patient reported sexual function outcomes in male patients following open radical cystoprostatectomy and urinary diversion. Urology, 2021, 157: 161-167. doi: 10.1016/j.urology.2021.07.004. Google Scholar
[3]
Hernández V, Castillón Vela I.T, Gómez Rivas J et al. Sexual preserving cystectomy: a systematic review. Urol Oncol, 2017, 35 (6): e17-e27. doi: 10.1016/j.urolonc.2017.02.016. Google Scholar
[4]
Rosen R.C, Riley A, Wagner G, Osterloh I.H, Kirkpatrick J, Mishra A. The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction. Urology, 1997, 49 (6): 822-830. doi: 10.1016/S0090-4295(97)00238-0. Google Scholar
[5]
Hekal I.A, El-Bahnasawy M.S, Mosbah A, El-Assmy A, Shaaban A. Recoverability of erectile function in post-radical cystectomy patients: subjective and objective evaluations. Eur Urol, 2009, 55 (2): 275-283. doi: 10.1016/j.eururo.2008.06.072. Google Scholar
[6]
Zippe C.D, Raina R, Massanyi E.Z et al. Sexual function after male radical cystectomy in a sexually active population. Urology, 2004, 64 (4): 682-685. doi: 10.1016/j.urology.2004.05.056. Google Scholar
[7]
Aaronson N.K, Ahmedzai S, Bergman B et al. The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst, 1993, 85 (5): 365-376. doi: 10.1093/jnci/85.5.365. Google Scholar