Articles Vol. 67 No. CĐ7-Trường ĐH Y Dược Hải Phòng 06/07/2026

THE EFFECTIVENESS OF PAIN RELIEF AND SIDE EFFECTS OVER TIME OF THE CONTINUOUS EPIDURAL ANESTHESIA IN LABOR AT HAI PHONG OBSTETRICS HOSPITAL

Do Thi Lan Anh1,2, Nguyen Quang Loi3,4, Pham Thi Thu Huong2,5, Nguyen Thi Thu Huong2,5, Vu Van Quang2,5
1 Nursing faculty, Hai Phong university of Medicine and Pharmacy
2 Khoa Điều dưỡng, Trường Đại học Y Dược Hải Phòng.
3 Anesthesia and Resuscitation department, Hai Phong university of Medicine and Pharmacy.
4 Bộ môn Gây mê hồi sức, Trường Đại học Y Dược Hải Phòng.
5 Nursing faculty, Hai Phong university of Medicine and Pharmacy.
DOI: 10.52163/yhc.v67iCD7.5591
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Abstract

Objective: To evaluate the analgesic effectiveness and identify side effects over time of continuous epidural anesthesia (CEA) during labor.  

Research Method: A prospective observational study conducted on 115 women undergoing vaginal delivery at Hai Phong Obstetrics Hospital from January to April 2026. The women received continuous analgesia with a syringe pump delivering a mixture of 0.1% Levobupivacaine and 2 mcg/ml Fentanyl. Pain scores using VAS were assessed at four time points: before anesthesia, 30 minutes after anesthesia, at delivery, and during perineal suturing; side effects were monitored during labor and up to 48 hours postpartum.  

Results: Regarding pain relief, the average VAS score significantly decreased from 8.2 (before CEA) to 3.4 at 30 minutes post-anesthesia; at delivery, the VAS increased to 6.9 due to mechanical pressure in the pelvic area; then decreased to 2.5 during perineal suturing. Concerning side effects, during labor, the most common symptoms were chills (32.2%), leg numbness (22.6%), back pain (20%), and nausea (18.2%). However, after 48 hours, most of these symptoms disappeared or significantly decreased, with the low back pain rate reduced to only 9.5% and no serious complications observed.  

References
[1]
Bonarska M, Adasik D, Szymczyk S, Łocik G, Stanirowski P. A Systematic Review of Contemporary and Emerging Analgesia Techniques for Natural Labor–Patient-Centered Approaches and Technological Advances. JCM. 2025;14(11):3977. doi:10.3390/jcm14113977 Google Scholar
[2]
Đình Tuyến N, Tiến Dũng N. Nghiên cứu ứng dụng phương pháp gây tê ngoài màng cứng để giảm đau chuyển dạ cho sản phụ sinh thường tại Bệnh viện Sản-Nhi tỉnh Quảng Ngãi. VMJ. 2021;498(2). doi:10.51298/vmj.v498i2.206 Google Scholar
[3]
Phung QT, Cao NT, Truong QV. Research epidural analgesia to pain relief on labor progress. JMP. Published online June 2012:31-41. doi:10.34071/jmp.2012.3.6 Google Scholar
[4]
Yu R, Deng X, Hu N, Chen DX. Comparative effectiveness of diverse strategies for the prevention or treatment of epidural-related maternal fever: a systematic review and network meta-analysis of randomized controlled trials. American Journal of Obstetrics and Gynecology. 2025;233(6):581-590.e30. doi:10.1016/j.ajog.2025.07.029 Google Scholar
[5]
Halliday L, Nelson SM, Kearns RJ. Epidural analgesia in labor: A narrative review. Intl J Gynecology & Obste. 2022;159(2):356-364. doi:10.1002/ijgo.14175 Google Scholar
[6]
Hùng NC, Lam NĐ, Hoàng NC, Lợi ĐV. So sánh hiệu quả giảm đau trong chuyển dạ đẻ của gây tê ngoài màng cứng giữa truyền thuốc tê liên tục với tiêm ngắt quãng tự động. YHCĐ. 2026;67(1). doi:10.52163/yhc.v67i1.4112 Google Scholar
[7]
Anim-Somuah M, Smyth RM, Cyna AM, Cuthbert A. Epidural versus non-epidural or no analgesia for pain management in labour. Cochrane Pregnancy and Childbirth Group, ed. Cochrane Database of Systematic Reviews. 2018;2018(5). doi:10.1002/14651858.CD000331.pub4 Google Scholar
[8]
Cambic CR, Wong CA. Labour analgesia and obstetric outcomes. British Journal of Anaesthesia. 2010;105:i50-i60. doi:10.1093/bja/aeq311 Google Scholar
[9]
Macarthur, Alison J. MD, FRCPC; Macarthur, Colin MBChB, PhD; Weeks, Sally K. MBBS, FRCA. Is Epidural Anesthesia in Labor Associated with Chronic Low Back Pain? A Prospective Cohort Study. Anesthesia & Analgesia 85(5):p 1066-1070 Google Scholar