Articles Vol. 67 No. 6 25/06/2026

PREVALENCE OF HIGH RISK AND ASSOCIATED FACTORS AMONG PREGNANT WOMEN AT 11-13 WEEKS AND 6 DAYS OF GESTATION UNDERGOING PREECLAMPSIA SCREENING

Nguyen Thuy Thuy Ai1,2, Le Hong Thinh1,2, Pham Thi Thanh Thoang1,2, Le Thi My Hanh1,2, Ho Thi Kim Yen1,2, Bui Viet Sang1,2, Lam Duc Tam3,4, Le Thi Kim Dinh1,2
1 Can Tho city Obstetrics and Gynecology Hospital
2 Bệnh viện Phụ Sản thành phố Cần Thơ
3 Can Tho University of Medicine and Pharmacy
4 Trường Đại học Y Dược Cần Thơ
DOI: 10.52163/yhc.v67i6.5498
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Keywords
Preeclampsia, screening, high risk.
Abstract

Objective: To determine the prevalence of high-risk preeclampsia and associated factors among pregnant women at 11-13 weeks and 6 days of gestation at Can Tho city Obstetrics and Gynecology Hospital.

Methods: A cross-sectional analytical study was conducted on 1672 pregnant women undergoing preeclampsia screening at 11-13 weeks and 6 days of gestation at Can Tho city Obstetrics and Gynecology Hospital from November 2023 to April 2025. High-risk screening was performed using the PerkinElmer LifeCycle™ software (based on a Bayesian model), which has been validated by the Fetal Medicine Foundation for predicting the risk of preeclampsia. Logistic regression analysis was applied to identify factors associated with high-risk preeclampsia.

Results: The prevalence of high-risk preeclampsia was 7.1%. Significant associated factors included: civil servant occupation (OR = 1.638; p = 0.017), education level ≤ high school (OR = 1.696; p = 0.035), and nulliparity (OR = 2.071; p = 0.001). The risk increased with BMI = 23-24.9 kg/m² (OR = 1.962; p = 0.006) and BMI ≥ 25 kg/m² (OR = 2.345; p < 0.001).

Conclusions: The prevalence of high-risk preeclampsia among pregnant women at 11-13 weeks and 6 days of gestation was relatively high (7.1%). The main associated factors were BMI, nulliparity, and socio-demographic characteristics.

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