Articles Vol. 67 No. 6 25/06/2026

RESULTS OF LAPAROSCOPIC COLORECTAL RESECTION WITH NATURAL ORIFICE SPECIMEN EXTRACTION FOR COLORECTAL CANCER AT NGHE AN ONCOLOGY HOSPITAL

Quach Van Kien1,2, Nguyen Dinh Hieu1,2,3,4
1 Hanoi Medical University
2 Trường Đại học Y Hà Nội
3 Nghe An Oncology Hospital
4 Bệnh viện Ung bướu Nghệ An
DOI: 10.52163/yhc.v67i6.5479
22 Views
13 Downloads
Abstract

Objective: To evaluate the outcomes of laparoscopic colorectal resection with natural orifice specimen extraction (NOSE) in the treatment of colorectal cancer at Nghe An Oncology Hospital.

Methods: A retrospective descriptive study was conducted on 38 patients with colorectal cancer who underwent laparoscopic colorectal resection with natural orifice specimen extraction at Nghe An Oncology Hospital from January 2023 to October 2025. Data on tumor characteristics, surgical features, and intraoperative and postoperative outcomes were collected from medical records and analyzed using SPSS 26.0.

Results: The mean age was 56.4 ± 10.9 years, with a male-to-female ratio of 2.2/1. Tumors were most commonly located in the upper rectum (50%). Most patients were at T3 stage (71%) and had lymph node metastasis (73.7%). Anterior resection was performed in 65.8% of cases, and low anterior resection in 34.2%. Specimens were mainly extracted transanally (71.1%). The mean operative time was 139 ± 22 minutes. No intraoperative mortality, anastomotic leakage, or intra-abdominal abscess was recorded. Postoperatively, the mean pain score on postoperative day 2 was 3.2 ± 1.2. The mean time to flatus was 2.0 ± 0.8 days, time to oral intake was 1.5 ± 0.4 days, and length of hospital stay was 7.1 ± 0.7 days.

Conclusion: Laparoscopic colorectal resection with natural orifice specimen extraction is a feasible and safe technique with favorable short-term outcomes in the treatment of colorectal cancer at Nghe An Oncology Hospital.

References
[1]
Bray F, Laversanne M, Sung H et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin, 2024, 74 (3): 229-263. doi: 10.3322/caac.21834 Google Scholar
[2]
Mahmoud Y, Thiagarajan V, Jihad Y, Ranganatha A, Khalid F, Essani B. Comparing the outcomes of laparoscopic versus open surgery for colorectal cancer: a systematic review and meta-analysis. Cureus, 2025, 17 (8): e90687. doi:10.7759/cureus.90687 Google Scholar
[3]
Guan X, Liu Z, Longo A et al. International consensus on natural orifice specimen extraction surgery (NOSES) for colorectal cancer. Gastroenterol Rep, 2019, 7 (1): 24-31. doi: 10.1093/gastro/goy055 Google Scholar
[4]
Pompeu B.F, Mara Vieira Rocha V, Machado Oliveira A.F et al. Natural orifice specimen extraction for right-sided colon cancer: a systematic review and meta-analysis of propensity score-matched studies. Cureus, 2025, 17 (5): e84191. doi: 10.7759/cureus.84191 Google Scholar
[5]
Hồ Hữu Thiện, Phạm Như Hiệp và cộng sự. Lấy bệnh phẩm qua lỗ tự nhiên trong phẫu thuật nội soi điều trị ung thư đại trực tràng. Tạp chí Y học lâm sàng, Bệnh viện Trung ương Huế, 2014 (20): 26-31. Google Scholar
[6]
Vũ Xuân Vinh, Nguyễn Ngọc Hùng và cộng sự. Đánh giá kết quả phẫu thuật nội soi hoàn toàn điều trị ung thư đại trực tràng lấy bệnh phẩm qua đường tự nhiên tại Bệnh viện Bạch Mai. Tạp chí Y học Việt Nam, 2025, 547 (1): 5-10. doi: 10.51298/vmj.v547i1.12831 Google Scholar
[7]
Liu Y, Guan X, Xu Q et al. Evaluating the learning curves and surgical outcomes of natural orifice specimen extraction surgery (NOSES) for colorectal cancer: a retrospective analysis from a National Registry. Colorectal Dis Off J Assoc Coloproctology G B Irel, 2025, 27 (9): e70229. doi: 10.1111/codi.70229 Google Scholar
[8]
Wolthuis A.M, de Buck van Overstraeten A, D’Hoore A. Laparoscopic natural orifice specimen extraction-colectomy: a systematic review. World J Gastroenterol WJG, 2014, 20 (36): 12981-12992. doi: 10.3748/wjg.v20.i36.12981 Google Scholar
[9]
Ma B, Huang X.Z, Gao P et al. Laparoscopic resection with natural orifice specimen extraction versus conventional laparoscopy for colorectal disease: a meta-analysis. Int J Colorectal Dis, 2015, 30 (11): 1479-1488. doi: 10.1007/s00384-015-2337-0 Google Scholar
[10]
Jiang W, Xu J, Cui M et al. Laparoscopy-assisted versus open surgery for low rectal cancer (LASRE): 3-year survival outcomes of a multicentre, randomised, controlled, non-inferiority trial. Lancet Gastroenterol Hepatol, 2025, 10 (1): 34-43. doi: 10.1016/S2468-1253(24)00273-5 Google Scholar