Articles Vol. 67 No. CĐ6-NCKH 16/06/2026

FACTORS ASSOCIATED WITH VERY PRETERM AND EXTREMELY PRETERM INFANTS AT THAI NGUYEN CENTRAL HOSPITAL

Nguyen Thi Tam1,2, Nguyen Mai Huong3,4, Nguyen Thi Hien5,6
1 Department of Pediatrics, Vinmec Times City International Hospital, Vinmec Healthcare System
2 Khoa Nhi, Bệnh viện Đa khoa Quốc tế Vinmec Times City, Vinmec Healthcare System
3 YK 14-01 Class, Dai Nam University, Hanoi, Vietnam
4 Lớp YK 14-01 - Trường Đại học Đại Nam
5 Department of Family Medicine, Thai Nguyen University of Medicine and Pharmacy
6 Bộ môn Y học gia đình, Trường Đại học Y dược, Đại học Thái Nguyên
DOI: 10.52163/yhc.v67iCD6.5329
17 Views
0 Downloads
Abstract

Objective: To analyze factors associated with very preterm and extremely preterm birth among preterm infants at Thai Nguyen Central Hospital.

Methods: A cross-sectional descriptive study was conducted on 110 preterm infants (<37 weeks of gestation) at the Pediatric Center, Thai Nguyen Central Hospital.

Results: Maternal age ≥35 years, educational level at or below high school, and occupations such as farmers/workers were significantly associated with an increased risk of very preterm and extremely preterm birth (<32 weeks) (p < 0.05). Obstetric factors including ≤1 pregnancy, assisted conception, history of preterm birth, history of miscarriage/induced abortion, and maternal medical history were also significantly associated with very preterm and extremely preterm birth (p < 0.05).

Conclusion: Very preterm and extremely preterm birth are significantly associated with multiple maternal and obstetric risk factors. These findings highlight the importance of screening, monitoring, and management of high-risk pregnancies.

References
[1]
World Health Organization, Born too soon: decade of action on preterm birth. World Health Organization, 2023. Google Scholar
[2]
Hannah Blencowe et al., "National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications," (in eng), The lancet, vol. 379, no. 9832, pp. 2162-2172, 2012. doi: 10.1016/S0140-6736(12)60820-4 Google Scholar
[3]
Robert L Goldenberg et al., "Epidemiology and causes of preterm birth," (in eng), The lancet, vol. 371, no. 9606, pp. 75-84, 2018. doi: 10.1016/S0140-6736(08)60074-4 Google Scholar
[4]
Marie Delnord and Jennifer Zeitlin, "Epidemiology of late preterm and early term births–An international perspective," in Seminars in Fetal and Neonatal Medicine, 2019, vol. 24, no. 1, pp. 3-10: Elsevier. doi: 10.1016/j.siny.2018.09.001 Google Scholar
[5]
Saifon Chawanpaiboon et al., "Global, regional, and national estimates of levels of preterm birth in 2014: a systematic review and modelling analysis," (in eng), The Lancet global health, vol. 7, no. 1, pp. e37-e46, 2019. doi: 10.1016/S2214-109X(18)30451-0. Google Scholar
[6]
Nguyễn Hồng Được et al., "Đặc điểm bệnh tật và một số yếu tố liên quan ở trẻ sơ sinh non tháng dưới 34 tuần tuổi thai," (in vi), Tạp chí Y học Việt Nam, vol. 542, no. 1, 2024. https://doi.org/10.51298/vmj.v542i1.10997 Google Scholar
[7]
(2015). Quyết định số 315/QĐ-BYT Hướng dẫn chẩn đoán và điều trị các bệnh Sản Phụ khoa. Google Scholar
[8]
Trương Thiện Tiên et al., "Tình hình sinh non tại Bệnh viện Trường Đại học Y-Dược Huế," (in vi), Tạp chí Phụ sản, vol. 22, no. 3, pp. 38-43, 2024. doi: 10.46755/vjog.2024.3.1779 Google Scholar
[9]
Bộ Y Tế, "Hướng dẫn quốc gia về các dịch vụ chăm sóc sức khỏe sinh sản," (in Vi), Chảy máu trong nửa đầu thai kỳ, pp. 87-91, 2016. Google Scholar
[10]
M. Jiang et al., "A case control study of risk factors and neonatal outcomes of preterm birth," (in eng), Taiwan J Obstet Gynecol, vol. 57, no. 6, pp. 814-818, Dec 2018. doi: 10.1016/j.tjog.2018.10.008 Google Scholar
[11]
C. X. Ye et al., "Risk factors for preterm birth: a prospective cohort study," (in eng chi), Zhongguo Dang Dai Er Ke Za Zhi, vol. 23, no. 12, pp. 1242-1249, Dec 15 2021. 早产危险因素的前瞻性队列研究. doi: 10.7499/j.issn.1008-8830.2108015 Google Scholar
[12]
Bùi Thị Thúy, "Nghiên cứu đặc điểm lâm sàng, cận lâm sàng và tìm hiểu một số yếu tố liên quan đến đẻ non tại bệnh viện phụ sản Thanh Hóa năm 2013-2014," Chuyên khoa II, Sản Khoa, Trường Đại học Y Hà Nội, Hà Nội, 2014 Google Scholar
[13]
P. Cavoretto et al., "Risk of spontaneous preterm birth in singleton pregnancies conceived after IVF/ICSI treatment: meta-analysis of cohort studies," (in eng), Ultrasound Obstet Gynecol, vol. 51, no. 1, pp. 43-53, Jan 2018. doi: 10.1002/uog.18930. Google Scholar
[14]
Paolo Cavoretto et al., "Nuchal translucency measurement, free β‐hCG and PAPP‐A concentrations in IVF/ICSI pregnancies: systematic review and meta‐analysis," (in eng), Prenatal diagnosis, vol. 37, no. 6, pp. 540-555, 2017. doi: 10.1002/pd.5052 Google Scholar
[15]
P. Cavoretto et al., "First trimester combined screening test in pregnancies derived from blastocyst transfer," (in eng), Eur J Obstet Gynecol Reprod Biol, vol. 198, pp. 50-55, Mar 2016. doi: 10.1016/j.ejogrb.2015.12.026 Google Scholar
[16]
J. Morales-Roselló et al., "Abnormal Middle Cerebral Artery Doppler Associates with Spontaneous Preterm Birth in Normally Grown Fetuses," (in eng), Fetal Diagn Ther, vol. 40, no. 1, pp. 41-7, 2016. doi: 10.1159/000441519. Google Scholar
[17]
C. Defilipo É et al., "Factors associated with premature birth: a case-control study," (in eng por), Rev Paul Pediatr, vol. 40, p. e2020486, 2022. doi: 10.1590/1984-0462/2022/40/2020486IN. Google Scholar
[18]
M. Lemmers et al., "Dilatation and curettage increases the risk of subsequent preterm birth: a systematic review and meta-analysis," (in eng), Hum Reprod, vol. 31, no. 1, pp. 34-45, Jan 2016. doi: 10.1093/humrep/dev274 Google Scholar
[19]
涂鹏程 and 裴开颜, "人工流产后早产, 低出生体重和继发不孕发生风险的研究进展," (in eng chi), 生殖医学杂志, vol. 29, no. 2, pp. 268-271, 2020. https://doi.org/10.3389/fendo.2022.791229 Google Scholar