Articles Vol. 67 No. CĐ6-NCKH 16/06/2026

CLINICAL, PARACLINICAL CHARACTERISTICS AND TREATMENT OUTCOMES OF INFLUENZA A IN CHILDREN UNDER 5 YEARS OLD AT THE HAI DUONG GENERAL HOSPITAL

Nguyen Thi Thu Hien1,2, Pham Thi Tuyet Linh3,4, Le Hai Van3,4, Vu Thi Hoang Anh1,2
1 Hai Duong Medical Technical University
2 Trường Đại học Kỹ thuật Y tế Hải Dương
3 Hai Duong General Hospital
4 Bệnh viện Đa khoa Hải Dương
DOI: 10.52163/yhc.v67iCD6.5300
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Abstract

Objective: This study to describe the clinical, paraclinical characteristics and evaluate the treatment outcomes of influenza A in children under 5 years of age treated at the pediatric department in Hai Duong General Hospital.

Subjects: 40 children were diagnosed with influenza A and treated at the pediatric department in Hai Duong General Hospital from January 2025 to October 2025.

Methods: A retrospective and prospective, cross-sectional descriptive.

Results: the mean age of the study population was 34.2 ± 5.8 months, children aged from 12 to under 60 months were the most common, the male/female ratio was 1.86/1. The common clinical manifestation were fever (97.5%), cough (95%), and rhinorrhea (65%). Other symptoms such as headache, sore throat, myalgia, abdominal pain, vomiting were less common. The paraclinical showed that 50% of patients had leukocytosis and 15% had leukopenia, 55% of patients did not exhibit elevated CRP levels (<10 mg/L). The succeedly cured result was 100%. The averaged hospital-stayed period were 6.4 ± 2.4 days.

Conclusion: Children aged 12 to under 60 months were the most commonly affected age group among patients with influenza A. Clinical, paraclinical characteristics were generally non-specific. The most frequent complications were pneumonia and bronchitis. The mean treatment duration was 6.4 ± 2.4 days. Close monitoring of disease progression and early detection of complications are essential for timely management and to reduce treatment duration.

References
[1]
Bộ Y tế. Hướng dẫn chẩn đoán và điều trị một số bệnh truyền nhiễm (Ban hành kèm theo Quyết định số 5642/QĐ-BYT ngày 31/12/2015). Hà Nội: Nhà xuất bản Y học; 2016. tr.49-53. Google Scholar
[2]
Lê Thị Thanh Huyền. Đặc điểm dịch tễ học, lâm sàng, cận lâm sàng, biến chứng và kết quả điều trị bệnh cúm ở trẻ em tại Bệnh viện Đại học Y khoa Vinh. Tạp chí Y học Việt Nam. 2024;536(2):181-185. doi:10.51298/vmj.v536i2.10665. Google Scholar
[3]
Bùi Thị Thu Thủy, Nguyễn Thị Diệu Thúy, Nguyễn Thị Thu Hiền; Nguyễn Thị Hoàng Anh, Đặng Thị Hà. Dịch tễ học lâm sàng, cận lâm sàng bệnh cúm mùa ở trẻ em tại Bệnh viện Nhi Hải Dương. Tạp chí Y học Việt Nam. 2024;542(1):89-92. doi: 10.51298/vmj.v542i1.10951. Google Scholar
[4]
Chong Chia-Yin, Yung Chee-Fu, Gan Cherie, et al. The clinical features, diagnosis, and outcomes of influenza infection in children admitted to a tertiary pediatric hospital in an acute respiratory infections surveillance program. Influenza Other Respir Viruses. 2020;14:46-54. doi:10.1111/irv.12699. Google Scholar
[5]
Fu Shui, Zhang Miao-Miao, Zhang Liang, Wu Li-Feng, Hu Qi-Lei. The value of combined serum amyloid a protein and neutrophil-to-lymphocyte ratio testing in the diagnosis and treatment of influenza a in children. Int J Gen Med. 2021;14:3729-3735. doi:10.2147/IJGM.S313895. Google Scholar
[6]
Silvennoinen Heli, Peltola Ville, Lehtinen Pasi, Vainionpää Raija, Heikkinen Terho. Clinical presentation of influenza in unselected children treated as outpatients. Pediatr Infect Dis J. 2009;28(5):372-375. doi:10.1097/INF.0b013e318191eef7. Google Scholar
[7]
Wolf Ryan M, Antoon James W. Influenza in Children and Adolescents: Epidemiology, Management, and Prevention. Pediatr Rev. 2023;44(11):605-617. doi:10.1542/pir.2023-005962. Google Scholar
[8]
World Health Organization (2024) Influenza (seasonal). Google Scholar