Articles Vol. 63 No. chuyên đề 3-HN Sản Nhi Nghệ An (2022) 30/11/2022

THE DISTRIBUTION OF PNEUMOCOCCAL SEROTYPES CAUSES PNEUMONIA IN CHILDREN UNDER 5 YEARS OF AGE IN NGHE AN

Bui Anh Son1,2, Duong Dinh Chinh1,3, Tang Xuan Hai1,2, Le Thi Hong Hanh4,5, Tran Van Anh6,7
1 Nghe An Hospital of Obstetrics and Pediatrics
2 Bệnh viện Sản Nhi Nghệ An
3 Sở Y tế Nghệ An
4 Vietnam National Children’s Hospital
5 Bệnh viện Nhi Trung ương
6 Hanoi Medical University
7 Trường Đại học Y Hà Nội
Corresponding author: drsonres@gmail.com
DOI: 10.52163/yhc.v63i8.522
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Keywords
Community-acquired pneumonia, S.pneumonia, pneumococcal vaccine.
Abstract

Objective: To determine the distribution of pneumococcal serotypes in children under 5 years
old in Nghe An.
Methods: In this cross-sectional descriptive study, 160 nasalpharyngeal samples positive with
S. pneumonia were collected from children under five years old in Nghe An Obstetrics and
Gynecology Hospital from August 2020 to August 2022.
Result: 12 pneumococcal serotypes were identified, including: 19F (69.5%), 19A (7.5%), 9V
(4.4%), 9A (3.8%), 6A (2.5%), 20 (1.9%), 23A (1.2%), 15A (1.2%), 6B (1.2%), 34 (0.6%), 6C
(0.6 %), 33A/33F (0.6%), 34 (0.6%). There were 7 samples of other pneumococcal types (4.4%), 1
sample that similar sequences not found (0.6%). PCV13 covered 5 pneumococcal serotypes
(81.3%), while PCV7 and PCV10 covered 3 types (69.5%). PCV13 covered not only all PCV7 and
PCV10-related serotypes but also 6A and 19A serotype.
Conclusion: There were 12 pneumococcal serotypes identified and the most common serotypes
were 19F, 19A, 9A, 9V, and 6A. Most of the common serotypes are covered by pneumococcal
vaccines. In terms of vaccine coverage, PCV13 is more effective than PCV7 and PCV10.

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