Articles Vol. 67 No. 5 25/05/2026

REMINERALIZATION EFFICACY OF 1450 PPM SODIUM FLUORIDE ON A GROUP OF EARLY-STAGE CARIOUS PERMANENT TEETH IN CHILDREN AGED 6-15 YEARS ON NGOC VUNG ISLAND QUANG NINH PROVINCE IN 2025

Vu Manh Tuan1,2, Ta Thuy Loan1,2, Do Duc Phu1,2, Bui Thi Thanh Hai1,2, Hoang Thanh Tam1,2, Dang Cong Son3,4, Nguyen Duc Hoang1,2, Nguyen Viet Hung1,2, Luu Van Tuong5,6, Nguyen Thi Thu Huong7,8
1 Hanoi Medical University
2 Viện Đào tạo Răng Hàm Mặt, Trường Đại học Y Hà Nội
3 FPT Long Chau
4 FPT Long Châu
5 Faculty of Dentistry, University of Medicine and Pharmacy
6 Khoa Răng Hàm Mặt, Trường Đại học Y Dược, Đại học Quốc Gia Hà Nội
7 Faculty of Dentistry, Phenikaa Medical and Pharmaceutical University
8 Khoa Răng Hàm Mặt, Trường Y Dược Phenikaa, Đại học Phenikaa
DOI: 10.52163/yhc.v67i5.5179
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Keywords
Remineralization, early caries lesion, Sodium Fluoride 1450 ppm, toothpaste, Diagnodent, school oral health.
Abstract

Objectives: To evaluate the remineralization efficacy of 1450 ppm Sodium Fluoride (NaF) toothpaste on early caries lesion (ECL) of permanent teeth among students aged 6-15 on Ngoc Vung Island, Quang Ninh.

Subjects and methods: A non-controlled clinical intervention study with a before-after design was conducted on ECLs from 70 students. Participants were instructed to brush twice daily with 1450 ppm NaF toothpaste using the modified Bass technique under supervision for 6 months. Efficacy was assessed based on the change in severity of 33 ECLs (D1, D2 levels) measured by the Diagnodent 2190 device at baseline (T0) and after 6 months (T1). Data were analyzed using SPSS 26.0.

Results: After 6 months, the analysis of the 33 lesions showed that 12.5% of initial D1 lesions recovered completely (to D0) and 28.1% remained stable (D1). Among initial D2 lesions, 15.6% improved to D0 and 37.5% improved to D1. The remineralization effect was statistically significant and most pronounced in the molar region (p < 0.001).

Conclusion: The usage of 1450 ppm Sodium Fluoride toothpaste is effective in promoting remineralization, improving, and stabilizing early caries lesions on the permanent teeth of children, especially in high-risk areas like molars. This is a feasible and effective intervention for school-based oral health programs in disadvantaged areas such as islands.

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