Articles Vol. 67 No. 5 25/05/2026

CLINICAL AND PARACLINICAL CHARACTERISTICS OF PREGNANT WOMEN WITH TWIN PREGNANCIES ≥ 22 WEEKS DIAGNOSED WITH PREECLAMPSIA AT CAN THO GYNECOLOGY AND OBSTETRICS HOSPITAL, 2024-2026

Nguyen Anh Van1,2, Nguyen Quoc Tuan1,2, Thach Thao Dan Thanh1,2, Du Kim Chau3,4
1 Can Tho University of Medicine and Pharmacy
2 Trường Đại học Y Dược Cần Thơ
3 Can Tho Gynecology Obstetrics Hospital
4 Bệnh viện Phụ Sản thành phố Cần Thơ
DOI: 10.52163/yhc.v67i5.5150
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Keywords
Twin pregnancy, preeclampsia, preeclampsia with severe features, HELLP syndrome.
Abstract

Objective: To describe the clinical and paraclinical characteristics of pregnant women with twin pregnancies ≥ 22 weeks diagnosed with preeclampsia at Can Tho Gynecology Obstetrics Hospital from 2024 to 2026.

Subject and methods: A cross-sectional descriptive study was conducted on 44 pregnant women with twin pregnancies ≥ 22 weeks diagnosed with preeclampsia who were hospitalized for monitoring, treatment, and delivery at Can Tho Gynecology Obstetrics Hospital during the study period.

Results: The mean maternal age was 30.7 ± 5.6 years, with 81.8% aged under 35 years. The mean pre-pregnancy BMI was 22.8 ± 3.3 kg/m²; 38.6% had a BMI ≥ 23 kg/m². Conception via assisted reproductive technologies accounted for 38.6%. The mean gestational age at onset of preeclampsia was 37.7 ± 3.1 weeks; 38.6% had onset before 34 weeks. Preeclampsia with severe features occurred in 52.3% of cases, and HELLP syndrome in 15.9%. The highest recorded systolic blood pressure averaged 155.5 ± 16.5 mmHg. Among those with severe features, 87% had severe hypertension; hemolysis was observed in 34.8%, thrombocytopenia and elevated liver enzymes each in 17.4%, and renal impairment in 13%. No factors were statistically significantly associated with severe preeclampsia; however, all cases with chronic hypertension were classified as having severe features (p = 0.050).

Conclusion: Preeclampsia in twin pregnancies ≥ 22 weeks’ gestation was characterized by a high proportion of severe cases and a substantial rate of early-onset disease, accompanied by multiple manifestations of multi-organ involvement. Larger studies are warranted to further clarify predictors of severe disease.

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