Articles Vol. 67 No. 5 25/05/2026

ANALYSIS OF ROUTINE ELECTROENCEPHALOGRAPHIC ABNORMALITIES IN PATIENTS WITH CHRONIC ALCOHOL DEPENDENCE AND RELATED FACTORS

Do Xuan Tinh1,2, Nguyen Van Linh1,2, Le Van Quan1,2
1 Military Hospital 103
2 Bệnh viện Quân y 103
DOI: 10.52163/yhc.v67i5.5141
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Abstract

Objective: To describe clinical features and routine electroencephalogram findings, and to assess associations between electroencephalogram abnormalities and clinical factors in patients with chronic alcoholism.

Methods: A cross-sectional descriptive study was conducted on 67 patients with chronic alcoholism treated at the Department of Psychiatry, Military Hospital 103 from January 2023 to December 2025.

Results: The mean age was 45.8 ± 8.6 years; males accounted for 92.5% of the sample. A drinking duration of ≥ 10 years was observed in 65.7% of patients; the rates of alcohol withdrawal seizures and delirium tremens were 26.9% and 17.9%, respectively. The prevalence of abnormal electroencephalogram was 52.2%, with diffuse background slowing being the most common abnormality (35.8%). Abnormal electroencephalogram was significantly associated with age ≥ 45 years (OR = 4.22; p = 0.005), drinking duration ≥ 10 years (OR = 5.48; p = 0.002), average alcohol consumption ≥ 500 mL/day (OR = 3.03; p = 0.030), alcohol withdrawal seizures (OR = 4.67; p = 0.011), and delirium tremens (OR = 6.00; p = 0.017).

Conclusion: Electroencephalogram abnormalities were present in more than half of patients with chronic alcoholism, predominantly as diffuse background slowing. Older age, prolonged alcohol use, and severe withdrawal manifestations were associated with electroencephalogram abnormalities.

References
[1]
GBD 2016 Alcohol Collaborators. Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet, 2018, 392 (10152): 1015-1035. doi: 10.1016/S0140-6736(18)31310-2. Google Scholar
[2]
Becker H.C. Alcohol dependence, withdrawal, and relapse. Alcohol Res Health, 2008, 31 (4): 348-361. Google Scholar
[3]
Hillbom M, Pieninkeroinen I, Leone M. Seizures in alcohol-dependent patients: epidemiology, pathophysiology and management. CNS Drugs, 2003, 17 (14): 1013-1030. doi: 10.2165/00023210-200317140-00002. Google Scholar
[4]
Trevisan L.A, Boutros N, Petrakis I.L et al. Complications of alcohol withdrawal: pathophysiological insights. Alcohol Health Res World, 1998, 22 (1): 61-66. Google Scholar
[5]
Rangaswamy M, Porjesz B. Understanding alcohol use disorders with neuroelectrophysiology. Handb Clin Neurol, 2014, 125: 383-414. doi: 10.1016/B978-0-444-62619-6.00023-9. Google Scholar
[6]
Sullivan E.V, Pfefferbaum A. Neurocircuitry in alcoholism: a substrate of disruption and repair. Psychopharmacology (Berl), 2005, 180 (4): 583-594. doi: 10.1007/s00213-005-2267-6. Google Scholar
[7]
Lechtenberg R, Worner T.M. Seizure risk with recurrent alcohol detoxification. Arch Neurol, 1990, 47 (5): 535-538. doi: 10.1001/archneur.1990.00530050055012. Google Scholar
[8]
Duka T, Townshend J.M, Collier K et al. Impairment in cognitive functions after multiple detoxifications in alcoholic inpatients. Alcohol Clin Exp Res, 2003, 27 (10): 1563-1572. doi: 10.1097/01.ALC.0000090142.11260.D7. Google Scholar