Articles Vol. 63 No. chuyên đề 3-HN Sản Nhi Nghệ An (2022) 30/11/2022

CARBAPENEM RESISTANT ENTEROBACTERIACEA CARRIAGE AND TRANSMISSION AMONG SICK NEWBORN ADMITTED TO NGHE AN OBSTETRICS AND PEDIATRICS HOSPITAL, 2022

Tran Van Cuong1,2, Nguyen Thi Tam1,2, Truong Le Thi1,2, Hoang Thi Bich Ngoc3,4, Le Kien Ngai3,4
1 Nghe An Hospital of Obstetrics and Pediatrics
2 Bệnh viện Sản Nhi Nghệ An
3 Vietnam National Children’s Hospital
4 Bệnh viện Nhi Trung ương
Corresponding author: bstamk38@gmail.com
DOI: 10.52163/yhc.v63i8.514
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Keywords
CRE ( ), neonate, transmission, carrier.
Abstract

Objectives: To estimate the distribution, transmission rate, and the risk of transmission of
Carbapenem-resistant Enterobacteriaceae (CRE) isolated from newborns patients admitted to the
Nghe An Obstetrics and Pediatrics Hospital between June 2022 and July 2022.
Methods: A cohort study with screening for colonization with CRE was conducted on 156
newborns under 28 days old admitted to neonatal department, Nghe An Obstetrics and Pediatrics
Hospital between June 2022 and July 2022. CRE colonization was determined by culturing of
fecal specimens on Carba-smart medium for CRE. Risk factors for CRE transmission were
evaluated.
Results: The prevalence of CRE infections was 3.2% upon admission and 53.2% at discharge.
Fifty percent of patients with negative screening results for CRE were infected during the
hospitalized days. K. Pneumoniae agent was the leading cause of transmission. Sex, gestational
age, birth weight, respiratory failure, mechanical ventilation, and Oxygen inhalation are factors
associated with CRE transmission.
Conclusions: The prevalence of CRE infections increased during the hospitalized period.
K.Pneumoniae agent was the leading cause of transmission. Gestational age, sex, birth weight,
respiratory failure, mechanical ventilation, and oxygen inhalation

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