Articles Vol. 63 No. chuyên đề 3-HN Sản Nhi Nghệ An (2022) 30/11/2022

STUDY PLASMA SODIUM DISTURBANCES ON SEVERE TRAUMATIC BRAIN INJURY PATIENTS

Tang Xuan Hai1,2, Ta Thi Quynh Anh1,2, Le Thi Minh Hang1,2, Hoang Van Thang1,2
1 Nghe An Hospital of Obstetrics and Pediatrics
2 Bệnh viện Sản Nhi Nghệ An
Corresponding author: bstangxuanhai@gmail.com
DOI: 10.52163/yhc.v63i8.513
17 Views
0 Downloads
Keywords
Traumatic brain injury, pediatric patient, blood sodium level, hypernatremia, hyponatremia.
Abstract

Introduction: Traumatic brain injury (TBI) is a common emergency in . The severity of TBI is
determined by the damage as primary or secondary. Secondary injury might change TBI patients
from mild to severe and might become the main cause of death in these ones. Hypernatremia has
been considered as one of the main causes of secondary injury in TBI patients.
Objective: To detect changes of sodium levels in blood of pediatric patients who has TBI and
some factors related to these disorders.
Subjects and methods: A cross-sectional descriptive study, 88 patients in the group of
2months - 15years old. Results: The average rate of dysnatremia was 35%. Hyponatremia
represented 26%, hypernatremia represented 9%. Hypernatremia increases the number of days on
mechanical ventilation. Hypernatremia has a higher rate in the group of patients with severe TBI
(Glasgow ≤ 8 points) and complex injury on computed tomography (CT) of the brain.
Conclusions: Hyponatremia is more common than hypernatremia. However, the prevalence of
hypernatremia is higher in patients with severe TBI. In general, hyponatremia increases the
duration of mechanical ventilation, so it should be diagnosed and treated at the earliest.

References
[1]
CS, Basheer N, Alapatt JP et al., A Google Scholar
[2]
Prospective Study on Hyponatremia in Google Scholar
[3]
Traumatic Brain Injury. Indian J Neurotrauma, Google Scholar
[4]
(2), 94–100, 2016. Google Scholar
[5]
Ibrahim MA, Tanya CS, Hypernatremia Is Google Scholar
[6]
Associated with Increased Risk of Mortality in Google Scholar
[7]
Pediatric Severe Traumatic Brain Injury. Google Scholar
[8]
Journal of Neurotrauma. 30(5), 2012. Google Scholar
[9]
Arambula E, Reinl E, Demerdash E et al., Google Scholar
[10]
Sex Differences in Pediatric Traumatic Brain Google Scholar
[11]
Injury. Exp Neurol. 317, 168–179, 2019. Google Scholar
[12]
Ramanan R, Ganesh S, Shalini N et al., Google Scholar
[13]
Hyponatremia in Traumatic Brain Injury: A Google Scholar
[14]
Practical Management Protocol. World Google Scholar
[15]
Neurosurg. 108:529-533, 2017. Google Scholar
[16]
Moro N, Katayama Y, Igarashi T et al., Google Scholar
[17]
Hyponatremia in patients with traumatic brain Google Scholar
[18]
injury: incidence, mechanism, and response to Google Scholar
[19]
sodium supplementation or retention therapy Google Scholar
[20]
with hydrocortisone. Surg Neurol, 68(4), 387– Google Scholar
[21]
, 2017. Google Scholar
[22]
Lohani S, Devkota UP, Hyponatremia in Google Scholar
[23]
Patients with Traumatic Brain Injury: Etiology, Google Scholar
[24]
Incidence, and Severity Correlation. World Google Scholar
[25]
Neurosurgery, 76(3–4), 355–360, 2011. Google Scholar
[26]
Dr. Mahmood S, Dr. Mazin MJ, Dr. Saad Google Scholar
[27]
HK, Outcome analysis and outcome prognostic Google Scholar
[28]
factors of traumatic brain injury in childhood. Google Scholar
[29]
International Journal of Medicine and Google Scholar
[30]
Pharmaceutical Science, Vol. 9, Issue 4, 35-48, Google Scholar
[31]
Mwachaka P, Amayo A, Mwang’ombe N, Google Scholar
[32]
Association Between Serum Sodium Google Scholar
[33]
Abnormalities and Clinicoradiologic Google Scholar
[34]
Parameters in Severe Traumatic Brain Injury. Google Scholar
[35]
Annals of African Surgery, 18(3), 155–162, Google Scholar