Articles Vol. 67 No. English Version No 1, 2026 02/06/2026

ANTIMICROBIAL RESISTANCE PATTERNS AND SUSCEPTIBILITY PROFILES OF UROPATHOGENS AT TRA VINH GENERAL HOSPITAL

Tran Hoang Hieu1, Nguyen Thi Kieu Tien1, Nguyen Nhu Y1
1 Tra Vinh University
DOI: 10.52163/yhc.v67iE1.5103
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Keywords
Urinary tract infection, E. coli, K. pneumoniae, P. aeruginosa, Tra Vinh.
Abstract

Urinary tract infections (UTIs) are among the top five most common hospital-acquired infections. Annually, millions of patients are affected by healthcare-associated UTIs, posing a major challenge to medical facilities worldwide.

Objective: To determine the antimicrobial resistance patterns and susceptibility profiles of each uropathogen isolated from inpatients with suspected UTIs who underwent urine culture at Tra Vinh General Hospital.

Materials and Methods: A descriptive, retrospective cross-sectional study was conducted on 132 patients (or episodes). Bacterial strains were identified and antimicrobial susceptibility testing (AST) was performed using the Vitek 2 automated system. Data were recorded from medical records.

Results: E. coli exhibited high resistance rates of >80% to Ampicillin, Piperacillin, and Fluoroquinolones (Ciprofloxacin). Bacterial isolates were more frequent than fungi (23.48% vs 8.33%). K. pneumoniae demonstrated 100% resistance to Ampicillin, Ampicillin-sulbactam, Cefepime, and Cefoxitin; resistance to Carbapenems, Aminoglycosides, and Fluoroquinolones ranged from 80% to 100%; and resistance to Cephalosporins exceeded 66.67%. P. aeruginosa showed a 50% resistance rate to Piperacillin-tazobactam, Piperacillin, Ceftazidime, Imipenem, Meropenem, and Ciprofloxacin. P. mirabilis was 100% resistant to Ampicillin, Piperacillin, Ciprofloxacin, and Tigecycline.

Conclusion: It is essential to prioritize urine culture and antimicrobial susceptibility testing before antibiotic administration to guide appropriate treatment regimens, prevent misuse, and mitigate the risk of escalating antimicrobial resistance.

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