Articles Vol. 67 No. CĐ5-NCKH 04/05/2026

VALUE OF ULTRASOUND IN THE DIAGNOSIS OF PROSTATE CANCER IN PATIENTS AGED 50 YEARS AND OLDER AT MEDIC MEDICAL CENTER, 2020–2023

Diep Bao Tuan1,2, Nguyen Chi Cuong3,4, Nguyen Truong Vien5,6, Hoang Van Cuong7,8, Tran Moc Hiep3,4
1 Ho Chi Minh City Oncology Hospital
2 Bệnh viện Ung Bướu Thành phố Hồ Chí Minh
3 Medic Medical Center
4 Trung tâm Y khoa Medic
5 Pham Ngoc Thach University of Medicine
6 Trường Đại học Phạm Ngọc Thạch
7 Hong Bang International University
8 Trường Đại học Quốc tế Hồng Bàng
DOI: 10.52163/yhc.v67iCD5.4990
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Keywords
Prostate cancer; Prostate gland; Transrectal ultrasound; TRUS.
Abstract

Objective: To evaluate the diagnostic performance of transrectal ultrasound (TRUS) features in detecting prostate cancer in men aged ≥50 years at Medic Medical Center from 2020–2023.

Methods: A retrospective cross-sectional study was conducted on 583 medical records of men aged ≥50 years who were suspected of having prostate cancer based on abnormal digital rectal examination (DRE) findings or prostate-specific antigen (PSA) levels ≥4 ng/mL at Medic Medical Center from January 2020 to April 2023.

Results: The prevalence of prostate cancer in high-risk individuals was 39.8%. TRUS features, including abnormal nodules and heterogeneous echogenicity, showed the strongest associations with prostate cancer, with sensitivities of 91.8% and 91.4%, respectively, and a specificity of 83.2% for both. The multivariate regression model demonstrated excellent diagnostic performance (AUC = 0.921). Risk stratification combining abnormal nodules, irregular prostate capsule, and increased vascularity achieved a diagnostic accuracy of 95.4%.

Conclusion: TRUS demonstrates high diagnostic value for prostate cancer in high-risk individuals through a multivariate regression model with an AUC of 0.921. These findings confirm the important role of TRUS in risk stratification and in guiding prostate biopsy indications.

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